17β-hydroxysteroid dehydrogenases in the progression of nonalcoholic fatty liver disease
MX Wang, ZG Peng - Pharmacology & Therapeutics, 2023 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) has become a worldwide epidemic and a major
public health problem, with a prevalence of approximately 25%. The pathogenesis of …
public health problem, with a prevalence of approximately 25%. The pathogenesis of …
Phenyl dialkynylcarbinols, a Bioinspired Series of Synthetic Antitumor Acetylenic Lipids
M Bossuat, P Rullière, N Preuilh… - Journal of Medicinal …, 2023 - ACS Publications
A series of 25 chiral anti-cancer lipidic alkynylcarbinols (LACs) were devised by introducing
an (hetero) aromatic ring between the aliphatic chain and the dialkynylcarbinol warhead …
an (hetero) aromatic ring between the aliphatic chain and the dialkynylcarbinol warhead …
Exploring the chemical reactivity of triisopropylsilyl dialkynyl methanol for the synthesis of dialkynylcarbinol-related compounds
MV de Brito, FX Toublet, M Bossuat, DMB Davi… - 2024 - chemrxiv.org
Prompted by the pharmacological relevance of lipidic alkynylcarbinols, 1-(triisopropyl) silyl)
penta-1, 4-diyn-3-ol was exploited as a versatile C5 organic framework. Selective …
penta-1, 4-diyn-3-ol was exploited as a versatile C5 organic framework. Selective …
A modular concept for enzymatically activatable caged electrophiles & Chemoproteomic analysis of the covalent ligandability of Moraxella catarrhalis
M Zollo - 2023 - mediatum.ub.tum.de
Two complementary strategies to tackle the growing health crisis of antibiotic resistance
were pursued in this thesis. A modular concept of caged electrophiles that are selectively …
were pursued in this thesis. A modular concept of caged electrophiles that are selectively …