Cushing's syndrome

M Gadelha, F Gatto, LE Wildemberg, M Fleseriu - The Lancet, 2023 - thelancet.com
Endogenous Cushing's syndrome results from excess glucocorticoid secretion, which leads
to a myriad of clinical manifestations, comorbidities, and increased mortality despite …

[HTML][HTML] Current and Future Perspectives of Microscopic and Endoscopic Transsphenoidal Surgery for Pituitary Adenomas: A Narrative Review

G Guinto, GY Guinto-Nishimura… - Archives of Medical …, 2023 - Elsevier
Transsphenoidal resection remains the standard treatment for most pituitary adenomas.
However, the ideal surgical approach to safely access these lesions, either microsurgical or …

Ovine CRH stimulation and 8 mg dexamethasone suppression tests in 323 patients with ACTH-dependent Cushing's syndrome

H Elenius, R McGlotten… - The Journal of Clinical …, 2024 - academic.oup.com
Context Determining the etiology of adrenocorticotropin (ACTH)-dependent Cushing's
syndrome (CS) is often difficult. The gold standard test, inferior petrosal sinus sampling …

[HTML][HTML] Bilateral inferior petrosal sinus sampling: validity, diagnostic accuracy in lateralization of pituitary microadenoma, and treatment in eleven patients with …

MT Ardakani, S Rabizadeh, A Yadegar… - BMC Endocrine …, 2023 - Springer
Background This single-center retrospective cohort study aimed to describe the findings and
validity of Bilateral inferior petrosal sinus sampling (BIPSS) in the differential diagnosis of …

Is desmopressin useful in the evaluation of Cushing syndrome?

F Castinetti, A Lacroix - The Journal of Clinical Endocrinology & …, 2022 - academic.oup.com
The desmopressin test was first described 30 years ago. Based on the differential
secretagogue properties of desmopressin on adrenocorticotropin (ACTH) release between …

Bilateral inferior petrosal sinus sampling in the differential diagnosis of ACTH‐dependent Cushing's syndrome: A reappraisal

M Valizadeh, B Abiri, F Hosseinpanah… - Journal of Internal …, 2024 - Wiley Online Library
Cushing's syndrome (CS) is a rare disorder, once exogenous causes have been excluded.
However, when diagnosed, the majority of cases are adrenocorticotropic hormone (ACTH) …

Diagnostic work-up of ACTH-dependent Cushing's syndrome in the context of CRH shortage: recommendation of a task force from the European Society of …

A Colao, C Scaroni, E Mezösi, L Saiegh… - European Journal of …, 2024 - academic.oup.com
The main worldwide supplier recently stated that corticotropin-releasing hormone (CRH) is
not manufactured anymore. The European Society of Endocrinology established a task force …

The conundrum of differentiating Cushing's syndrome from non-neoplastic hypercortisolism: a systematic review and meta-analysis

JM Hinojosa-Amaya, FD González-Colmenero… - Pituitary, 2024 - Springer
Context Once hypercortisolemia is confirmed, differential diagnosis between Cushing's
syndrome (CS) due to neoplastic endogenous hypercortisolism and non-neoplastic …

[HTML][HTML] Pitfalls in the diagnosis and management of hypercortisolism (Cushing syndrome) in humans; a review of the laboratory medicine perspective

KC Flowers, KE Shipman - Diagnostics, 2023 - mdpi.com
Biochemical confirmation of a diagnosis of hypercortisolism (Cushing syndrome) is vital to
direct further investigations, especially given the overlap with non-autonomous conditions …

Alternative Approach to BIPSS in the Differential Diagnosis of ACTH-Dependent Cushing Syndrome

M Gadelha, LE Wildemberg - The Journal of Clinical …, 2024 - academic.oup.com
Cushing syndrome (CS) is a very complex disease, which may need an intricate diagnostic
work-up. It can be due to adrenocorticotrophic hormone (ACTH)–dependent (70-80%) or …