Brain function critically depends on a close matching between metabolic demands,
appropriate delivery of oxygen and nutrients, and removal of cellular waste. This matching …

Cerebral autoregulation (CA) refers to the control of cerebral tissue blood flow (CBF) in
response to changes in perfusion pressure. Due to the challenges of measuring intracranial …

Acute stroke is associated with high morbidity and mortality. In the last decades, new
therapies have been investigated with the aim of improving clinical outcomes in the acute …

Optimizing cerebral perfusion is key to rescuing salvageable ischemic brain tissue. Despite
being an important determinant of cerebral perfusion, there are no effective guidelines for …

Cerebral autoregulation (CA) prevents brain injury by maintaining a relatively constant
cerebral blood flow despite fluctuations in cerebral perfusion pressure. This process is …

Restoring perfusion to ischemic tissue is the primary goal of acute ischemic stroke care, yet
only a small portion of patients receive reperfusion treatment. Since blood pressure (BP) is …

Objective Loss of cerebral autoregulation (CA) plays a key role in secondary neurologic
injury. However, the regional distribution of CA impairment after acute cerebral injury …

Ischemic stroke (IS) is one of the most impacting diseases in the world. In the last decades,
new therapies have been introduced to improve outcomes after IS, most of them aiming for …

The brain's ability to maintain cerebral blood flow approximately constant despite cerebral
perfusion pressure changes is known as cerebral autoregulation (CA) and is governed by …

Cerebral autoregulation refers to the physiological mechanism that aims to maintain blood
flow to the brain approximately constant when blood pressure changes. Impairment of this …