Unlocking inaccessible historical genomes preserved in formalin

EE Hahn, MR Alexander, A Grealy… - Molecular Ecology …, 2022 - Wiley Online Library
Museum specimens represent an unparalleled record of historical genomic data. However,
the widespread practice of formalin preservation has thus far impeded genomic analysis of a …

Reframing Formalin: A Molecular Opportunity Enabling Historical Epigenomics and Retrospective Gene Expression Studies

CE Holleley, EE Hahn - Molecular Ecology Resources, 2025 - Wiley Online Library
Formalin preservation of museum specimens has long been considered a barrier to
molecular research due to extensive crosslinking and chemical modification. However …

Investigation of CTNNB1 gene mutations and expression in hepatocellular carcinoma and cirrhosis in association with hepatitis B virus infection

D Javanmard, M Najafi, MR Babaei… - Infectious Agents and …, 2020 - Springer
Hepatitis B virus (HBV), along with Hepatitis C virus chronic infection, represents a major risk
factor for hepatocellular carcinoma (HCC) development. However, molecular mechanisms …

Historical DNA metabarcoding of the prey and microbiome of trematomid fishes using museum samples

FM Heindler, H Christiansen, B Frédérich… - Frontiers in Ecology …, 2018 - frontiersin.org
Antarctic specimens collected during various research expeditions are preserved in natural
history collections around the world potentially offering a cornucopia of morphological and …

[HTML][HTML] Utility and applicability of a universal set of primers in identifying the sex of South and Southeast Asian mammals

BD Joshi, R De, SP Goyal - Zoological Studies, 2019 - ncbi.nlm.nih.gov
Sex identification of individuals is an important task in wildlife forensics as well as in
conservation biology. It helps scientists understand population sex ratios with respect to …

Non-invasive sampling: reliable methods for DNA extraction and PCR amplification from a single scale of small Cyprinidae fish

BD Joshi, JA Johnson, SP Goyal, T Negi… - Zoology and …, 2018 - Taylor & Francis
The present study was aimed to DNA extraction and PCR amplification of mitochondrial
DNA of a varied size range using the non-invasive samples of fish. As many obstacles arise …

[PDF][PDF] Molecular genetic assessment of formalin-fixed ethanol-preserved King Cobra: A comparative study on pretreatment protocols and DNA extraction methods

S Suntrarachun, L Chanhome - Asian Journal of Conservation Biology, 2017 - ajcb.in
Four different pretreatment protocols for formalin-fixed ethanol-preserved (FFEP) King Cobra
(Ophiophagus hannah) specimens were tested to remove excess formalin before DNA …

[PDF][PDF] Utility and applicability of a universal set of primers in identifying the sex of South and Southeast Asian

BD Joshi, R De, SP Goyal - 2019 - academia.edu
Sex identification of individuals is an important task in wildlife forensics as well as in
conservation biology. It helps scientists understand population sex ratios with respect to …

[引用][C] Utility and applicability of a universal set of primers in identifying the sex of

BD Joshi, R De, SP Goyal - 2019