Flow-induced reprogramming of endothelial cells in atherosclerosis
Atherosclerotic diseases such as myocardial infarction, ischaemic stroke and peripheral
artery disease continue to be leading causes of death worldwide despite the success of …
artery disease continue to be leading causes of death worldwide despite the success of …
Overview of microRNA biology
In considering an overview of microRNA biology, it is useful to consider microRNAs as a part
of cellular communication. At the simplest level, microRNAs act to decrease the expression …
of cellular communication. At the simplest level, microRNAs act to decrease the expression …
The promising role of miR-21 as a cancer biomarker and its importance in RNA-based therapeutics
D Bautista-Sánchez, C Arriaga-Canon… - … Therapy-Nucleic Acids, 2020 - cell.com
MicroRNAs are small noncoding transcripts that posttranscriptionally regulate gene
expression via base-pairing complementarity. Their role in cancer can be related to tumor …
expression via base-pairing complementarity. Their role in cancer can be related to tumor …
microRNA-382 as a tumor suppressor? Roles in tumorigenesis and clinical significance
MicroRNAs (miRNAs) are small single-stranded RNAs belonging to a class of non-coding
RNAs with an average length of 18–22 nucleotides. Although not able to encode any …
RNAs with an average length of 18–22 nucleotides. Although not able to encode any …
Noncoding RNA s in disease
E Lekka, J Hall - FEBS letters, 2018 - Wiley Online Library
Noncoding RNA s are emerging as potent and multifunctional regulators in all biological
processes. In parallel, a rapidly growing number of studies has unravelled associations …
processes. In parallel, a rapidly growing number of studies has unravelled associations …
The role of miR‐21 in cancer
SR Pfeffer, CH Yang, LM Pfeffer - Drug development research, 2015 - Wiley Online Library
ABSTRACT Preclinical Research MicroRNAs (miRNAs) are small endogenous noncoding
RNAs that suppress gene expression at the post‐transcriptional level. In the past decade …
RNAs that suppress gene expression at the post‐transcriptional level. In the past decade …
New concepts in cancer biomarkers: circulating miRNAs in liquid biopsies
The effective and efficient management of cancer patients relies upon early diagnosis and/or
the monitoring of treatment, something that is often difficult to achieve using standard tissue …
the monitoring of treatment, something that is often difficult to achieve using standard tissue …
Mesenchymal stromal cells-derived exosomes alleviate ischemia/reperfusion injury in mouse lung by transporting anti-apoptotic miR-21-5p
J wei Li, L Wei, Z Han, Z Chen - European Journal of Pharmacology, 2019 - Elsevier
Abstract MiR-21-5p is an anti-apoptotic miRNA known to mediate the protective effect of
mesenchymal stromal cell-secreted exosomes (MSC-Exo) against oxidative stress-induced …
mesenchymal stromal cell-secreted exosomes (MSC-Exo) against oxidative stress-induced …
Milk is not just food but most likely a genetic transfection system activating mTORC1 signaling for postnatal growth
BC Melnik, SM John, G Schmitz - Nutrition journal, 2013 - Springer
Milk has been recognized to represent a functionally active nutrient system promoting
neonatal growth of mammals. Cell growth is regulated by the nutrient-sensitive kinase …
neonatal growth of mammals. Cell growth is regulated by the nutrient-sensitive kinase …
Different modalities of host cell death and their impact on Mycobacterium tuberculosis infection
Mycobacterium tuberculosis (Mtb) is the pathogen that causes tuberculosis (TB), a leading
infectious disease of humans worldwide. One of the main histopathological hallmarks of TB …
infectious disease of humans worldwide. One of the main histopathological hallmarks of TB …