[HTML][HTML] Recent applications of mixture designs in beverages, foods, and pharmaceutical health: A systematic review and meta-analysis
Design of Experiments (DoE) is a statistical tool used to plan and optimize experiments and
is seen as a quality technology to achieve products excellence. Among the experimental …
is seen as a quality technology to achieve products excellence. Among the experimental …
Predictive models of FDM 3D printing using experimental design based on pharmaceutical requirements for tablet production
The present study aimed to analyze how the printing process affects the final state of a
printed pharmaceutical product and to establish prediction models for post-printing …
printed pharmaceutical product and to establish prediction models for post-printing …
[HTML][HTML] Effect of physical stimuli on hair follicle deposition of clobetasol-loaded Lipid Nanocarriers
T Angelo, N El-Sayed, M Jurisic, A Koenneke… - Scientific reports, 2020 - nature.com
Clobetasol propionate (CLO) is a potent glucocorticoid used to treat inflammation-based
skin, scalp, and hair disorders. In such conditions, hair follicles (HF) are not only the target …
skin, scalp, and hair disorders. In such conditions, hair follicles (HF) are not only the target …
Lipid nanoparticles as carriers of cyclodextrin inclusion complexes: A promising approach for cutaneous delivery of a volatile essential oil
Solid inclusion complexes with cyclodextrins (CD) may be used to overcome volatility and
solubility problems of essential oils of pharmacological interest. However, they lack the …
solubility problems of essential oils of pharmacological interest. However, they lack the …
Nanostructured lipid carriers loaded with an association of minoxidil and latanoprost for targeted topical therapy of alopecia
PM Oliveira, T Alencar-Silva, FQ Pires… - European Journal of …, 2022 - Elsevier
Alopecia is a condition associated with different etiologies, ranging from hormonal changes
to chemotherapy, that affects over 80 million people in the USA. Nevertheless, there are …
to chemotherapy, that affects over 80 million people in the USA. Nevertheless, there are …
[HTML][HTML] Surface-modified multifunctional thymol-loaded biodegradable nanoparticles for topical acne treatment
C Folle, N Díaz-Garrido, E Sánchez-López… - Pharmaceutics, 2021 - mdpi.com
The present work is focused on the development of novel surface-functionalized poly (lactic-
co-glycolic acid) nanoparticles loaded with thymol (TH-NPs) for topical administration …
co-glycolic acid) nanoparticles loaded with thymol (TH-NPs) for topical administration …
Hydroxypropyl-β-cyclodextrin-complexed naringenin by solvent change precipitation for improving anti-inflammatory effect in vivo
The flavonoid naringenin (NAR) exhibits an outstanding anti-inflammatory potential;
however, stability problems and reduced solubility hinder its commercial insertion. This work …
however, stability problems and reduced solubility hinder its commercial insertion. This work …
Application of hot-melt extrusion in the complexation of naringenin with cyclodextrin using hydrophilic polymers
PA Granados, LAG Pinho, LL Sa-Barreto… - Advanced Powder …, 2022 - Elsevier
The complexation of cyclodextrin ranks among the best methods of overcoming the
unfavorable pharmacokinetic properties of naringenin (NAR). This work proposes obtaining …
unfavorable pharmacokinetic properties of naringenin (NAR). This work proposes obtaining …
Development of lipid polymer hybrid drug delivery systems prepared by hot-melt extrusion
FE Kasbaum, DM de Carvalho… - AAPS …, 2023 - Springer
This study sought to develop polymer-lipid hybrid solid dispersions containing the poorly
soluble drug lopinavir (LPV) by hot-melt extrusion (HME). Hence, the lipid and polymeric …
soluble drug lopinavir (LPV) by hot-melt extrusion (HME). Hence, the lipid and polymeric …
Hot melt-extrusion improves the properties of cyclodextrin-based poly (pseudo) rotaxanes for transdermal formulation
RN Marreto, G Cardoso, B dos Santos Souza… - International Journal of …, 2020 - Elsevier
This study aimed to investigate whether hot-melt extrusion (HME) processing can modify the
interactions between drugs, cyclodextrins and polymers, and in turn alter the microstructure …
interactions between drugs, cyclodextrins and polymers, and in turn alter the microstructure …