Early environmental risk factors for neurodevelopmental disorders–a systematic review of twin and sibling studies

T Carlsson, F Molander, MJ Taylor… - Development and …, 2021 - cambridge.org
While neurodevelopmental disorders (NDDs) are highly heritable, several environmental
risk factors have also been suggested. However, the role of familial confounding is unclear …

Prenatal exposure to maternal smoking during pregnancy and attention-deficit/hyperactivity disorder in offspring: a meta-analysis

T Dong, W Hu, X Zhou, H Lin, L Lan, B Hang, W Lv… - Reproductive …, 2018 - Elsevier
Some large population-based cohort studies highlighted the risk of maternal smoking during
pregnancy (MSDP) for children attention-deficit/hyperactivity disorder (ADHD). However, the …

Association between DNA methylation and ADHD symptoms from birth to school age: a prospective meta-analysis

A Neumann, E Walton, S Alemany, C Cecil… - Translational …, 2020 - nature.com
Attention-deficit and hyperactivity disorder (ADHD) is a common childhood disorder with a
substantial genetic component. However, the extent to which epigenetic mechanisms play a …

Prenatal cotinine levels and ADHD among offspring

A Sourander, M Sucksdorff, R Chudal, HM Surcel… - …, 2019 - publications.aap.org
OBJECTIVES: An association between maternal smoking during pregnancy and offspring
attention-deficit/hyperactivity disorder (ADHD) has been shown across several studies …

Developmental nicotine exposure precipitates multigenerational maternal transmission of nicotine preference and ADHD-like behavioral, rhythmometric …

JM Buck, KN Sanders, CR Wageman, VS Knopik… - …, 2019 - Elsevier
Maternal smoking during pregnancy, a form of developmental nicotine exposure (DNE), is
associated with increased nicotine use and neurodevelopmental disorders such as ADHD in …

DNA methylation as a potential mediator of the association between prenatal tobacco and alcohol exposure and child neurodevelopment in a South African birth …

S Abrishamcar, J Chen, D Feil, A Kilanowski… - Translational …, 2022 - nature.com
Prenatal tobacco exposure (PTE) and prenatal alcohol exposure (PAE) have been
associated with an increased risk of delayed neurodevelopment in children as well as …

Prenatal substance exposure and offspring development: Does DNA methylation play a role?

VS Knopik, K Marceau, LC Bidwell, E Rolan - Neurotoxicology and …, 2019 - Elsevier
The period of in utero development is one of the most critical windows during which adverse
conditions and exposures may influence the growth and development of the fetus as well as …

Maternal nicotine exposure alters hippocampal microglia polarization and promotes anti-inflammatory signaling in juvenile offspring in mice

L Zhou, X Tao, G Pang, M Mu, Q Sun, F Liu… - Frontiers in …, 2021 - frontiersin.org
Accumulating evidence reveal that maternal smoking or perinatal nicotine replacement
therapy impairs hippocampal neurogenesis, neural development, and cognitive behaviors in …

Developmental nicotine exposure elicits multigenerational disequilibria in proBDNF proteolysis and glucocorticoid signaling in the frontal cortices, striata, and …

JM Buck, HC O'Neill, JA Stitzel - Biochemical pharmacology, 2019 - Elsevier
Maternal smoking of conventional or vapor cigarettes during pregnancy, a form of
developmental nicotine exposure (DNE), enhances the risk of neurodevelopmental …

Family-based designs that disentangle inherited factors from pre-and postnatal environmental exposures: in vitro fertilization, discordant sibling pairs, maternal versus …

A Thapar, F Rice - Cold Spring Harbor …, 2021 - perspectivesinmedicine.cshlp.org
Identifying environmental risk and protective exposures that have causal effects on health is
an important scientific goal. Many environmental exposures are nonrandomly allocated and …