Inspired by the biological processes of molecular recognition and transportation across
membranes, nanopore techniques have evolved in recent decades as ultrasensitive …

Biological protein pores and pore-forming peptides can generate a pathway for the flux of
ions and other charged or polar molecules across cellular membranes. In nature, these …

There are still unmet needs in finding new technologies for biomedical diagnostic and
industrial applications. A technology allowing the analysis of size and sequence of short …

The chemical nature and precise position of posttranslational modifications (PTMs) in
proteins or peptides are crucial for various severe diseases, such as cancer. State-of-the-art …

As nanometer-scale portals in biological membranes, protein ionic channels act as
gatekeepers, controlling the traffic of ions and macromolecules into and out of cells …

Conformational heterogeneity is emerging as a defining characteristic of enzyme function.
However, understanding the role of protein conformations requires their thermodynamic and …

In this review, recent research efforts that aimed at developing nanopore sensors for
detection of metal ions, which play a crucial role in environmental safety and human health …

Proteins subjected to an electric field and forced to pass through a nanopore induce
blockades of ionic current that depend on the protein and nanopore characteristics and …

In two decades, the solid state and polymer nanopores became attractive method for the
protein sensing with high specificity and sensitivity. They also allow the characterization of …

Microorganisms have gained defense systems during the lengthy process of evolution over
millions of years. Such defense systems can protect them from being attacked by invading …