Transcriptomics for child and adolescent tuberculosis

M Kaforou, C Broderick, O Vito, M Levin… - Immunological …, 2022 - Wiley Online Library
Tuberculosis (TB) in humans is caused by Mycobacterium tuberculosis (Mtb). It is estimated
that 70 million children (< 15 years) are currently infected with Mtb, with 1.2 million each year …

Serum miRNA signatures are indicative of skeletal fractures in postmenopausal women with and without type 2 diabetes and influence osteogenic and adipogenic …

U Heilmeier, M Hackl, S Skalicky… - Journal of Bone and …, 2016 - academic.oup.com
Standard DXA measurements, including Fracture Risk Assessment Tool (FRAX) scores,
have shown limitations in assessing fracture risk in Type 2 Diabetes (T2D), underscoring the …

Computational biology in microRNA

Y Li, Z Zhang - Wiley Interdisciplinary Reviews: RNA, 2015 - Wiley Online Library
MicroRNA (miRNA) is a class of small endogenous noncoding RNA species, which regulate
gene expression post‐transcriptionally by forming imperfect base‐pair at the 3 …

miR‑27b‑3p and miR‑607 cooperatively regulate BLM gene expression by directly targeting the 3'‑UTR in PC3 cells

Y Chen, J Zhao, Z Duan, T Gong… - Molecular …, 2019 - spandidos-publications.com
BLM RecQ like helicase (BLM) has a pivotal role in genetic recombination, transcription,
DNA replication and DNA repair, which presents the possibility of using BLM as an anti …

Fibroblast miR-210 overexpression is independently associated with clinical failure in Prostate Cancer – a multicenter (in situ hybridization) study

S Andersen, E Richardsen, L Moi, T Donnem… - Scientific reports, 2016 - nature.com
There is a need for better prognostication in prostate cancer (PC).“The micromanager of
hypoxia”, microRNA-210 (miR-210) is directly linked to hypoxia, is overexpressed in PC and …

Multifaceted enrichment analysis of RNA–RNA crosstalk reveals cooperating micro-societies in human colorectal cancer

T Mazza, G Mazzoccoli, C Fusilli… - Nucleic acids …, 2016 - academic.oup.com
Alterations in the balance of mRNA and microRNA (miRNA) expression profiles contribute to
the onset and development of colorectal cancer. The regulatory functions of individual …

Impact of pri-let-7a-1 rs10739971 for Gastric Cancer Predisposition in an Amazon Region

RB Andrade, AN Cohen-Paes, DFVB Leal… - Genes, 2023 - mdpi.com
Gastric cancer (GC) is the fifth most common type of cancer and the fourth leading cause of
cancer death. In Brazil, GC has a high incidence and mortality rates, and it is highly variable …

The upregulation of hypoxia-related miRNA 210 in primary tumor of lymphogenic metastatic prostate cancer

O Eminaga, J Fries, S Neiß, M Heitmann, F Wötzel… - …, 2018 - Taylor & Francis
Aim: To show the association between the expression level of hsa-miR-210 (miR-210) and
tumor progression in prostate cancer (PCa). Methods: Quantitative PCR was performed to …

Reconstruction of temporal activity of microRNAs from gene expression data in breast cancer cell line

ND Jayavelu, N Bar - BMC genomics, 2015 - Springer
Background MicroRNAs (miRNAs) are small non-coding RNAs that regulate genes at the
post-transcriptional level in spatiotemporal manner. Several miRNAs are identified as …

Biomarker development for pancreatic ductal adenocarcinoma using integrated analysis of mRNA and miRNA expression

MS Kwon, Y Kim, S Lee, J Namkung… - 2014 IEEE …, 2014 - ieeexplore.ieee.org
Pancreatic ductal adenocarcinoma (PDAC) is the most common type of pancreatic cancer,
which has dismal prognosis because of its silent early symptoms, high metastatic potential …