The principal source of vitamin D in humans is its biosynthesis in the skin through a
chemical reaction dependent on sun exposure. In lesser amounts, the vitamin can be …

Abstract The 2 nd International Conference on Controversies in Vitamin D was held in
Monteriggioni (Siena), Italy, September 11-14, 2018. The aim of this meeting was to address …

Background The effect of supplementing unscreened adults with vitamin D 3 on mortality is
unclear. We aimed to determine whether monthly doses of vitamin D 3 influenced mortality …

Vitamin D deficiency (serum 25-hydroxyvitamin D (25 (OH) D)< 50 nmol/L or 20 ng/mL) is
common in Europe and the Middle East. It occurs in< 20% of the population in Northern …

Importance Vitamin D and calcium supplements are recommended for the prevention of
fracture, but previous randomized clinical trials (RCTs) have reported conflicting results, with …

Context Over the last decade, vitamin D has emerged as a risk determinant for type 2
diabetes and vitamin D supplementation has been hypothesized as a potential intervention …

Vitamin D represents a group of secosteroids involved in the calcium and phosphate
metabolism. The active form of vitamin D, 1, 25-dihydroxylcalciferol, exerts its biological …

Background Low circulating vitamin D levels are associated with poor colorectal cancer
(CRC) survival. We assess whether vitamin D supplementation improves CRC survival …

Whether supplemental vitamin D reduces risk of cancer or cardiovascular disease (CVD) is
relatively unexplored in randomized trial settings. The VITamin D and OmegA-3 TriaL …

Objective To determine if circulating concentrations of vitamin D are causally associated with
risk of cancer. Design Mendelian randomisation study. Setting Large genetic epidemiology …