Short-chain fatty acids in diseases

D Zhang, YP Jian, YN Zhang, Y Li, LT Gu… - Cell Communication and …, 2023 - Springer
Short-chain fatty acids (SCFAs) are the main metabolites produced by bacterial fermentation
of dietary fibre in the gastrointestinal tract. The absorption of SCFAs is mediated by substrate …

[HTML][HTML] Dual role of microbiota-derived short-chain fatty acids on host and pathogen

R Mirzaei, E Dehkhodaie, B Bouzari, M Rahimi… - Biomedicine & …, 2022 - Elsevier
A growing body of documents shows microbiota produce metabolites such as short-chain
fatty acids (SCFAs) as crucial executors of diet-based microbial influence the host and …

The function of gut microbiota in immune-related neurological disorders: A review

P Sittipo, J Choi, S Lee, YK Lee - Journal of Neuroinflammation, 2022 - Springer
This review provides an overview of the importance of microbiota in the regulation of gut–
brain communication in immune-related neurological disorders. The gastrointestinal (GI) …

Gut microbiota-derived short-chain fatty acids: impact on cancer treatment response and toxicities

GH Al-Qadami, KR Secombe, CB Subramaniam… - Microorganisms, 2022 - mdpi.com
The gut microbiota has emerged as a key modulator of cancer treatment responses in terms
of both efficacy and toxicity. This effect is clearly mediated by processes impacting the …

[HTML][HTML] Mediterranean diet and olive oil, microbiota, and obesity-related cancers. From mechanisms to prevention.

E Almanza-Aguilera, A Cano, M Gil-Lespinard… - Seminars in Cancer …, 2023 - Elsevier
Olive oil (OO) is the main source of added fat in the Mediterranean diet (MD). It is a mix of
bioactive compounds, including monounsaturated fatty acids, phytosterols, simple phenols …

Role of the gut microbiota in hematologic cancer

P Guevara-Ramírez, S Cadena-Ullauri… - Frontiers in …, 2023 - frontiersin.org
Hematologic neoplasms represent 6.5% of all cancers worldwide. They are characterized by
the uncontrolled growth of hematopoietic and lymphoid cells and a decreased immune …

[HTML][HTML] Role of microbiota short-chain fatty acids in the pathogenesis of autoimmune diseases

A Rasouli-Saravani, K Jahankhani, S Moradi… - Biomedicine & …, 2023 - Elsevier
There is emerging evidence that microbiota and its metabolites play an important role in
helath and diseases. In this regard, gut microbiota has been found as a crucial component …

[HTML][HTML] The impact of microbiota-derived short-chain fatty acids on macrophage activities in disease: Mechanisms and therapeutic potentials

H Duan, LJ Wang, M Huangfu, H Li - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Short-chain fatty acids (SCFAs) derived from the fermentation of carbohydrates by gut
microbiota play a crucial role in regulating host physiology. Among them, acetate …

Short-chain fatty acids—a product of the microbiome and its participation in two-way communication on the microbiome-host mammal line

O Lange, M Proczko-Stepaniak, A Mika - Current obesity reports, 2023 - Springer
Abstract Purpose of Review The review aims to describe short-chain fatty acids (SCFAs) as
metabolites of bacteria, their complex influence on whole-body metabolism, and alterations …

[HTML][HTML] Metabolites as extracellular vesicle cargo in health, cancer, pleural effusion, and cardiovascular diseases: An emerging field of study to diagnostic and …

Y Zhang, F Liang, DD Zhang, S Qi, Y Liu - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Extracellular vesicles (EVs) are highly diverse nanoscale membrane-bound structures
released from different cell types into the extracellular environment. They play essential …