The microbiota living in gut influences the immune response, metabolism, mood and
behavior. The diet plays a pivotal role in maintaining healthy gut microbiota composition and …

Type 2 diabetes (T2D) is one of the most common chronic metabolic disorders in adulthood
worldwide, whose pathophysiology includes an abnormal immune response accompanied …

Zingiber officinale is being used as diet-based therapy because of its wide therapeutic
potential in type 2 diabetes mellitus (T2DM) and against diabetic complications by directly …

Introduction Pro-inflammatory cytokines, such as interleukin (IL)-6, tumour necrosis factor
(TNF) α, and monocyte chemoattractant protein (MCP)-1, are often elevated in individuals …

Visceral obesity is a major risk factor for the development of insulin resistance which can
progress to overt type 2 diabetes (T2D) with loss of β‐cell function and, ultimately, loss of β …

A hallmark of type 2 diabetes mellitus (T2DM) is the presence of extracellular amyloid
deposits in the islets of Langerhans. These deposits are formed by the human islet amyloid …

The molecular mechanisms underlying obesity-induced increases in β cell mass and the
resulting β cell dysfunction need to be elucidated further. Our study revealed that GPR92 …

Proinflammatory cytokines have been implicated in the pathophysiology of both type 1
diabetes (T1D) and type 2 diabetes (T2D). T1D is an autoimmune disease involving the …

Pathology driving β-cell loss in diabetes is poorly defined. Chronic subclinical inflammation
is associated with β-cell dysfunction. Acute in vitro exposure of islets and β-cells to an …

Impaired glucose tolerance (IGT) and β-cell dysfunction in insulin resistance associated with
obesity lead to type 2 diabetes (T2D). Glucose-stimulated insulin secretion (GSIS) from β …