[HTML][HTML] CRISPR Cpf1 proteins: structure, function and implications for genome editing

F Safari, K Zare, M Negahdaripour… - Cell & bioscience, 2019 - Springer
CRISPR and CRISPR-associated (Cas) protein, as components of microbial adaptive
immune system, allows biologists to edit genomic DNA in a precise and specific way …

MicroRNAs in breast cancer: Roles, functions, and mechanism of actions

M Abolghasemi, SS Tehrani, T Yousefi… - Journal of cellular …, 2020 - Wiley Online Library
Breast cancer is one of the most lethal malignancies in women in the world. Various factors
are involved in the development and promotion of the malignancy; most of them involve …

Long non‐coding RNAs as potential biomarkers in the prognosis and diagnosis of lung cancer: A review and target analysis

Y Aftabi, K Ansarin, D Shanehbandi, M Khalili… - IUBMB …, 2021 - Wiley Online Library
Long non‐coding RNAs (lncRNA) have been emerged as a novel class of molecular
regulators in cancer. They are dysregulated in many types of cancer; however, there is not …

The interaction of phages and bacteria: the co-evolutionary arms race

F Safari, M Sharifi, S Farajnia, B Akbari… - Critical reviews in …, 2020 - Taylor & Francis
Since the dawn of life, bacteria and phages are locked in a constant battle and both are
perpetually changing their tactics to overcome each other. Bacteria use various strategies to …

Critical roles of long noncoding RNAs in breast cancer

M Abolghasemi, SS Tehrani, T Yousefi… - Journal of cellular …, 2020 - Wiley Online Library
Breast cancer is a major clinical challenge that affects a wide range of the female population
and heavily burdens the health system. In the past few decades, attempts have been made …

Alpha7 nicotinic acetylcholine receptors in lung inflammation and carcinogenesis: Friends or foes?

K Hajiasgharzadeh, S Sadigh‐Eteghad… - Journal of cellular …, 2019 - Wiley Online Library
The lung tissue expresses the cholinergic system including nicotinic acetylcholine receptors
(nAChRs) which included in many physiologic and pathologic processes. Mounting …

MicroRNA-486-5p improves nonsmall-cell lung cancer chemotherapy sensitivity and inhibits epithelial–mesenchymal transition by targeting twinfilin actin binding …

X Jin, W Pang, Q Zhang… - Journal of International …, 2019 - journals.sagepub.com
Objective To investigate the role of microRNA-486-5p (miR-486-5p) in nonsmall-cell lung
cancer (NSCLC) resistance to cisplatin. Methods This retrospective study examined tumours …

Anticancer Impacts of Terminalia catappa Extract on SW480 Colorectal Neoplasm Cell Line

D Shanehbandi, H Zarredar, M Asadi, V Zafari… - Journal of …, 2021 - Springer
Purpose Colorectal cancer (CRC) is one of the most lethal and prevalent cancers throughout
the world. Despite the remarkable advance in the field, drug resistance still remains as an …

Synergistic effect of novel EGFR inhibitor AZD8931 and p38α siRNA in lung adenocarcinoma cancer cells

H Zarredar, S Farajnia, K Ansarin… - Anti-Cancer Agents …, 2019 - ingentaconnect.com
Background: Lung cancer is the leading cause of cancer-related death with less than 5-year
survival rate for both men and women worldwide. EGFR and MAPK signaling pathways …

Identification of circulating miR-762 as a novel diagnostic and prognostic biomarker for non-small cell lung cancer

L Chen, Y Li, J Lu - Technology in cancer research & …, 2020 - journals.sagepub.com
Background: MicroRNAs (miRNAs) have been demonstrated to play critical roles in
tumorigenesis of non-small cell lung cancer (NSCLC), and circulating miRNAs are a …