New insights into establishment and maintenance of DNA methylation imprints in mammals
Fundamental to genomic imprinting in mammals is the acquisition of epigenetic marks that
differ in male and female gametes at 'imprinting control regions'(ICRs). These marks mediate …
differ in male and female gametes at 'imprinting control regions'(ICRs). These marks mediate …
Imprinted microRNA gene clusters in the evolution, development, and functions of mammalian placenta
EC Malnou, D Umlauf, M Mouysset, J Cavaillé - Frontiers in genetics, 2019 - frontiersin.org
In mammals, the expression of a subset of microRNA (miRNA) genes is governed by
genomic imprinting, an epigenetic mechanism that confers monoallelic expression in a …
genomic imprinting, an epigenetic mechanism that confers monoallelic expression in a …
Loss of H3K27me3 imprinting in the Sfmbt2 miRNA cluster causes enlargement of cloned mouse placentas
K Inoue, N Ogonuki, S Kamimura, H Inoue… - Nature …, 2020 - nature.com
Somatic cell nuclear transfer (SCNT) in mammals is an inefficient process that is frequently
associated with abnormal phenotypes, especially in placentas. Recent studies …
associated with abnormal phenotypes, especially in placentas. Recent studies …
Endogenous retroviral insertions drive non-canonical imprinting in extra-embryonic tissues
Background Genomic imprinting is an epigenetic phenomenon that allows a subset of genes
to be expressed mono-allelically based on the parent of origin and is typically regulated by …
to be expressed mono-allelically based on the parent of origin and is typically regulated by …
Genomic imprinting in the human placenta
D Monk - American journal of obstetrics and gynecology, 2015 - Elsevier
With the launch of the National Institute of Child Health and Human Development/National
Institutes of Health Human Placenta Project, the anticipation is that this often-overlooked …
Institutes of Health Human Placenta Project, the anticipation is that this often-overlooked …
Long-lasting alterations to DNA methylation and ncRNAs could underlie the effects of fetal alcohol exposure in mice
BI Laufer, K Mantha, ML Kleiber… - Disease models & …, 2013 - journals.biologists.com
Fetal alcohol spectrum disorders (FASDs) are characterized by life-long changes in gene
expression, neurodevelopment and behavior. What mechanisms initiate and maintain these …
expression, neurodevelopment and behavior. What mechanisms initiate and maintain these …
Noncanonical imprinting sustains embryonic development and restrains placental overgrowth
Genomic imprinting regulates parental origin-dependent monoallelic gene expression. It is
mediated by either germline differential methylation of DNA (canonical imprinting) or oocyte …
mediated by either germline differential methylation of DNA (canonical imprinting) or oocyte …
The miR‐379/miR‐410 cluster at the imprinted Dlk1‐Dio3 domain controls neonatal metabolic adaptation
S Labialle, V Marty, ML Bortolin‐Cavaillé… - The EMBO …, 2014 - embopress.org
In mammals, birth entails complex metabolic adjustments essential for neonatal survival.
Using a mouse knockout model, we identify crucial biological roles for the miR‐379/miR …
Using a mouse knockout model, we identify crucial biological roles for the miR‐379/miR …
Re-investigation and RNA sequencing-based identification of genes with placenta-specific imprinted expression
H Okae, H Hiura, Y Nishida, R Funayama… - Human molecular …, 2012 - academic.oup.com
Within the vertebrate groups, only mammals are subject to a specialized epigenetic process
termed genomic imprinting in which genes are preferentially expressed from one parental …
termed genomic imprinting in which genes are preferentially expressed from one parental …
Strategies to improve the efficiency of somatic cell nuclear transfer
Mammalian oocytes can reprogram differentiated somatic cells into a totipotent state through
somatic cell nuclear transfer (SCNT), which is known as cloning. Although many mammalian …
somatic cell nuclear transfer (SCNT), which is known as cloning. Although many mammalian …