Salmonella versus the Microbiome
AWL Rogers, RM Tsolis… - … and Molecular Biology …, 2021 - Am Soc Microbiol
SUMMARY A balanced gut microbiota contributes to health, but the mechanisms
maintaining homeostasis remain elusive. Microbiota assembly during infancy is governed by …
maintaining homeostasis remain elusive. Microbiota assembly during infancy is governed by …
Cancer and the microbiota
WS Garrett - Science, 2015 - science.org
A host's microbiota may increase, diminish, or have no effect at all on cancer susceptibility.
Assigning causal roles in cancer to specific microbes and microbiotas, unraveling host …
Assigning causal roles in cancer to specific microbes and microbiotas, unraveling host …
Salmonella SPI-2 type III secretion system effectors: molecular mechanisms and physiological consequences
E Jennings, TLM Thurston, DW Holden - Cell host & microbe, 2017 - cell.com
Serovars of Salmonella enterica cause both gastrointestinal and systemic diseases in a
broad range of mammalian hosts, including humans. Salmonella virulence depends in part …
broad range of mammalian hosts, including humans. Salmonella virulence depends in part …
Genome-guided design of a defined mouse microbiota that confers colonization resistance against Salmonella enterica serovar Typhimurium
S Brugiroux, M Beutler, C Pfann, D Garzetti… - Nature …, 2016 - nature.com
Protection against enteric infections, also termed colonization resistance, results from
mutualistic interactions of the host and its indigenous microbes. The gut microbiota of …
mutualistic interactions of the host and its indigenous microbes. The gut microbiota of …
Same species, different diseases: how and why typhoidal and non-typhoidal Salmonella enterica serovars differ
Human infections by the bacterial pathogen Salmonella enterica represent major disease
burdens worldwide. This highly ubiquitous species consists of more than 2600 different …
burdens worldwide. This highly ubiquitous species consists of more than 2600 different …
Regulation of bacterial virulence by Csr (Rsm) systems
Most bacterial pathogens have the remarkable ability to flourish in the external environment
and in specialized host niches. This ability requires their metabolism, physiology, and …
and in specialized host niches. This ability requires their metabolism, physiology, and …
Antimicrobial resistance and management of invasive Salmonella disease
Invasive Salmonella infections (typhoidal and non-typhoidal) cause a huge burden of illness
estimated at nearly 3.4 million cases and over 600,000 deaths annually especially in …
estimated at nearly 3.4 million cases and over 600,000 deaths annually especially in …
Evolution of bacterial virulence
Bacterial virulence is highly dynamic and context-dependent. For this reason, it is
challenging to predict how molecular changes affect the growth of a pathogen in a host and …
challenging to predict how molecular changes affect the growth of a pathogen in a host and …
Patterns of genome evolution that have accompanied host adaptation in Salmonella
GC Langridge, M Fookes, TR Connor… - Proceedings of the …, 2015 - National Acad Sciences
Many bacterial pathogens are specialized, infecting one or few hosts, and this is often
associated with more acute disease presentation. Specific genomes show markers of this …
associated with more acute disease presentation. Specific genomes show markers of this …
Distinct Salmonella Enteritidis lineages associated with enterocolitis in high-income settings and invasive disease in low-income settings
An epidemiological paradox surrounds Salmonella enterica serovar Enteritidis. In high-
income settings, it has been responsible for an epidemic of poultry-associated, self-limiting …
income settings, it has been responsible for an epidemic of poultry-associated, self-limiting …