Potential therapeutic targets of resveratrol, a plant polyphenol, and its role in the therapy of various types of cancer
Cancer is among the most prominent causes of mortality worldwide. Different cancer therapy
modes employed, including chemotherapy and radiotherapy, have been reported to be …
modes employed, including chemotherapy and radiotherapy, have been reported to be …
Broad-spectrum preclinical antitumor activity of chrysin: current trends and future perspectives
ER Moghadam, HL Ang, SE Asnaf, A Zabolian… - Biomolecules, 2020 - mdpi.com
Pharmacological profile of phytochemicals has attracted much attention to their use in
disease therapy. Since cancer is a major problem for public health with high mortality and …
disease therapy. Since cancer is a major problem for public health with high mortality and …
Biodegradable and dissolvable resveratrol nanocrystals non-silicon microneedles for transdermal drug delivery
Y Liu, Z Zhang, C Wang, X Xie, Y Ma, Y Wang - Journal of Drug Delivery …, 2023 - Elsevier
The prevalence and lethality of cutaneous melanoma have increased in recent years. Lower
skin penetration rates and poor soluble affect the effective delivery of resveratrol. To …
skin penetration rates and poor soluble affect the effective delivery of resveratrol. To …
Multiple effects of resveratrol on osteosarcoma cell lines
A De Luca, D Bellavia, L Raimondi, V Carina, V Costa… - Pharmaceuticals, 2022 - mdpi.com
Osteosarcoma (OS) is the most common primary bone sarcoma affecting the life of pediatric
patients. The clinical treatment faces numerous difficulties, including the adverse effects of …
patients. The clinical treatment faces numerous difficulties, including the adverse effects of …
Shedding light on the interaction of polydatin and resveratrol with G-quadruplex and duplex DNA: A biophysical, computational and biological approach
Among polyphenols, trans-resveratrol (tRES) and trans-polydatin (tPD) exert multiple
biological effects, particularly antioxidant and antiproliferative. In this work, we have …
biological effects, particularly antioxidant and antiproliferative. In this work, we have …
Melanoma Cellular Signaling Transduction Pathways Targeted by Polyphenols Action Mechanisms
Melanoma is the most aggressive type of skin cancer. Although different anti-melanoma
treatments are available, their efficacy is still improvable, and the number of deaths …
treatments are available, their efficacy is still improvable, and the number of deaths …
Cynaroside Induces G1 Cell Cycle Arrest by Downregulating Cell Division Cycle 25A in Colorectal Cancer
S Lei, W Cao, Z Zeng, L Wang, J Lan, T Chen - Molecules, 2024 - mdpi.com
Natural chemicals derived from herbal plants have recently been recognized as potentially
useful treatment alternatives owing to their ability to target a wide range of important …
useful treatment alternatives owing to their ability to target a wide range of important …
Pterostilbene-mediated inhibition of cell proliferation and cell death induction in amelanotic and melanotic melanoma
J Wawszczyk, K Jesse, M Kapral - International Journal of Molecular …, 2023 - mdpi.com
Melanoma is one of the fastest-growing cancers worldwide. Treatment of advanced
melanoma is very difficult; therefore, there is growing interest in the identification of new …
melanoma is very difficult; therefore, there is growing interest in the identification of new …
Porcupine quills keratin peptides induces G0/G1 cell cycle arrest and apoptosis via p53/p21 pathway and caspase cascade reaction in MCF‐7 breast cancer cells
K Wang, Y Xu, H Huang, D Peng… - Journal of the …, 2024 - Wiley Online Library
BACKGROUND Porcupine quills, a by‐product of porcupine pork, are rich in keratin, which
is an excellent source of bioactive peptides. The objective of this study was to investigate the …
is an excellent source of bioactive peptides. The objective of this study was to investigate the …
Screening of anti-melanoma compounds from Morus alba L.: Sanggenon C promotes melanoma cell apoptosis by disrupting intracellular Ca2+ homeostasis
X Hu, J Li, L Yu, J Ifejola, Y Guo, D Zhang… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Morus alba L. is a widespread plant that has long been
considered to have remarkable medical values, including anti-inflammation in Traditional …
considered to have remarkable medical values, including anti-inflammation in Traditional …