The quest for a respiratory syncytial virus vaccine for older adults: Thinking beyond the F protein

VA Jenkins, B Hoet, H Hochrein, L De Moerlooze - Vaccines, 2023 - mdpi.com
Respiratory syncytial virus (RSV) is a common cause of paediatric respiratory tract infection
and causes a significant health burden in older adults. Natural immunity to RSV is …

Vaccination against community-acquired pneumonia in spanish adults: practical recommendations by the NeumoExperts prevention group

E Redondo, I Rivero-Calle, E Mascarós, D Ocaña… - Antibiotics, 2023 - mdpi.com
In the adult population, community-acquired pneumonia (CAP) is a serious disease that is
responsible for high morbidity and mortality rates, being frequently associated with multidrug …

Respiratory syncytial virus infection: old challenges and new approaches

O Ramilo, R Rodriguez-Fernandez… - The Journal of …, 2023 - academic.oup.com
Respiratory syncytial virus (RSV) is an orthopneumovirus that belongs to the
Pneumoviridiae family. There are 2 antigenic subgroups, A and B, which can cocirculate …

Safety and immunogenicity of a revaccination with a respiratory syncytial virus prefusion F vaccine in older adults: a phase 2b study

I Leroux-Roels, M Van Ranst… - The Journal of …, 2024 - academic.oup.com
Background In the previous (parent) study, 2 doses of different formulations of an
investigational vaccine against respiratory syncytial virus (RSVPreF3 OA) were well …

Structural basis for respiratory syncytial virus and human metapneumovirus neutralization

RJ Miller, JJ Mousa - Current Opinion in Virology, 2023 - Elsevier
Respiratory syncytial virus (RSV) and human metapneumovirus (hMPV) continue to be a
global burden to infants, the elderly, and immunocompromised individuals. In the past ten …

Rate of hospitalizations and mortality of respiratory syncytial virus infection compared to influenza in older people: a systematic review and meta-analysis

S Maggi, N Veronese, M Burgio, G Cammarata… - Vaccines, 2022 - mdpi.com
Respiratory Syncytial Virus (RSV) is commonly regarded as an infection typical of children,
but increasing literature is showing its importance in older people. Since the data regarding …

Immunogenicity, Reactogenicity, and Safety of AS01E-adjuvanted Respiratory Syncytial Virus (RSV) Prefusion F Protein-based Candidate Vaccine (RSVPreF3 OA) …

R Chandler, N Montenegro, C Llorach… - Clinical Infectious …, 2024 - academic.oup.com
Background Co-administration of vaccines against respiratory syncytial virus (RSV) and
influenza can be considered given their overlapping seasonality and may increase vaccine …