Intranasal Drug Delivery by Nanotechnology: Advances in and Challenges for Alzheimer's Disease Management

S Dighe, S Jog, M Momin, S Sawarkar, A Omri - Pharmaceutics, 2023 - mdpi.com
Alzheimer's disease, a progressive neurodegenerative condition, is characterized by a
gradual decline in cognitive functions. Current treatment approaches primarily involve the …

Carbon dots as nanotherapeutics for biomedical application

EN Cohen, PPD Kondiah, YE Choonara… - Current …, 2020 - ingentaconnect.com
Carbon nanodots are zero-dimensional spherical allotropes of carbon and are less than
10nm in size (ranging from 2-8nm). Based on their biocompatibility, remarkable water …

Microfluidic synthesis of ultrasmall chitosan/graphene quantum dots particles for intranasal delivery in Alzheimer's disease treatment

F Mohebichamkhorami, M Faizi, M Mahmoudifard… - Small, 2023 - Wiley Online Library
Nanoparticles (NPs) based therapies for Alzheimer's disease (AD) attract interest due to
their ability to pass across or bypass the blood‐brain barrier. Chitosan (CS) NPs or …

Cur-loaded ZnFe2O4@ mZnO@ N-GQDs biocompatible nano-carriers for smart and controlled targeted drug delivery with pH-triggered and ultrasound irradiation

M Hafezi, M Rostami, A Hosseini… - Journal of Molecular …, 2021 - Elsevier
In the present study a pH/ultrasound (US)-responsive nano-carriers based on magnetic core-
shell ZnFe 2 O 4@ mZnO@ GQDs and ZnFe 2 O 4@ mZnO@ N-GQDs ternary composite …

Graphene quantum dots: preparations, properties, functionalizations and applications

P Tian, L Tang, KS Teng, SP Lau - Materials Futures, 2024 - iopscience.iop.org
Zero-dimensional graphene quantum dots (GQDs) exhibit many different properties, such as
strong fluorescence, nonzero bandgap and solubility in solvents, compared to two …

[HTML][HTML] Applications of carbon dots for the treatment of Alzheimer's disease

F Guo, Q Li, X Zhang, Y Liu, J Jiang… - International Journal …, 2022 - ncbi.nlm.nih.gov
There are currently approximately 50 million victims of Alzheimer's disease (AD) worldwide.
The exact cause of the disease is unknown at this time, but amyloid plaques and …

Pharmaceutical applications of quantum dots

A Gour, S Ramteke, NK Jain - AAPS PharmSciTech, 2021 - Springer
Nanotechnology has been utilized in developing novel drug formulations with minimal
adverse effects. Nanoparticles in a lower size range with great surface area, increased …

Thermodynamic investigation of the interaction between ionic liquid functionalized gold nanoparticles and human serum albumin for selective determination of …

S Sahu, S Sharma, I Karbhal, KK Ghosh - RSC advances, 2020 - pubs.rsc.org
The excellent biocompatible and monodispersed gold nanoparticles (AuNPs) functionalized
by amino based ionic liquid (IL) have been synthesized for the demonstration of their …

An in-silico approach: identification of PPAR-γ agonists from seaweeds for the management of Alzheimer's Disease

S Kotha, VM Kulkarni - Journal of Biomolecular Structure and …, 2021 - Taylor & Francis
Alzheimer's Disease is a complex progressive neurodegenerative disorder characterized by
neurofibrillary tangles and senile plaques in various parts of the brain particularly cerebral …

Multi-spectroscopic monitoring of molecular interactions between an amino acid-functionalized ionic liquid and potential anti-Alzheimer's drugs

S Sharma, MK Banjare, N Singh, J Korábečný… - RSC …, 2020 - pubs.rsc.org
Inhibiting the formation of amyloid fibrils is a crucial step in the prevention of the human
neurological disorder, Alzheimer's disease (AD). Ionic liquid (IL) mediated interactions are …