Reduced FSH and LH action: implications for medically assisted reproduction

E Bosch, C Alviggi, M Lispi, A Conforti… - Human …, 2021 - academic.oup.com
Luteinizing hormone (LH) and follicle-stimulating hormone (FSH) play complementary roles
in follicle development and ovulation via a complex interaction in the hypothalamus, anterior …

The development of gonadotropins for clinical use in the treatment of infertility

B Lunenfeld, W Bilger, S Longobardi, V Alam… - Frontiers in …, 2019 - frontiersin.org
The first commercially available gonadotropin product was a human chorionic gonadotropin
(hCG) extract, followed by animal pituitary gonadotropin extracts. These extracts were …

The POSEIDON criteria and its measure of success through the eyes of clinicians and embryologists

SC Esteves, C Alviggi, P Humaidan… - Frontiers in …, 2019 - frontiersin.org
This article represents a viewpoint on the POSEIDON criteria by a group of clinicians and
embryologists. Its primary objective is to contextualize the Poseidon criteria and their metric …

Update on the management of poor ovarian response in IVF: the shift from Bologna criteria to the Poseidon concept

P Drakopoulos, E Bardhi, L Boudry… - Therapeutic …, 2020 - journals.sagepub.com
Despite the considerate progress to which assisted reproduction technology (ART) has been
subject since 1978, some issues remain unresolved. Notably, the clinical management of …

Cumulative delivery rate per aspiration IVF/ICSI cycle in POSEIDON patients: a real-world evidence study of 9073 patients

SC Esteves, H Yarali, LN Vuong… - Human …, 2021 - academic.oup.com
STUDY QUESTION What is the cumulative delivery rate (CDR) per aspiration IVF/ICSI cycle
in low-prognosis patients as defined by the Patient-Oriented Strategies Encompassing …

Management of women with an unexpected low ovarian response to gonadotropin

A Conforti, SC Esteves, D Cimadomo… - Frontiers in …, 2019 - frontiersin.org
POSEIDON groups 1 and 2 patients respond poorly (< 4 oocytes retrieved) or sub-optimally
(4–9 oocytes retrieved) to gonadotropin stimulation despite the presence of adequate …

Management strategies for POSEIDON groups 3 and 4

T Haahr, C Dosouto, C Alviggi, SC Esteves… - Frontiers in …, 2019 - frontiersin.org
In the POSEIDON classification, patients belonging to groups 3 and 4 share the same
common feature of a poor ovarian reserve which independently of age renders them at high …

A novel predictive model to estimate the number of mature oocytes required for obtaining at least one euploid blastocyst for transfer in couples undergoing in vitro …

SC Esteves, JF Carvalho, FC Bento… - Frontiers in …, 2019 - frontiersin.org
The POSEIDON group (P atient-O riented S trategies E ncompassing I ndividualize DO ocyte
N umber) has introduced “the ability to retrieve the number of oocytes needed to achieve at …

Cumulative live birth rates in low-prognosis women

JA Leijdekkers, MJC Eijkemans… - Human …, 2019 - academic.oup.com
STUDY QUESTION Do cumulative live birth rates (CLBRs) over multiple IVF/ICSI cycles
confirm the low prognosis in women stratified according to the POSEIDON criteria …

What is the best regimen for ovarian stimulation of poor responders in ART/IVF?

Z Blumenfeld - Frontiers in endocrinology, 2020 - frontiersin.org
The infertile patients with aging ovaries—also sometimes referred to as impending
premature ovarian insufficiency (POI), impending premature ovarian failure (POF), or poor …