MicroRNA biogenesis, gene silencing mechanisms and role in breast, ovarian and prostate cancer
Micro-ribonucleic acids (miRNAs) are important class of short regulatory RNA molecules
involved in regulation of several essential biological processes. In addition to Dicer and …
involved in regulation of several essential biological processes. In addition to Dicer and …
DDX5 and DDX17—multifaceted proteins in the regulation of tumorigenesis and tumor progression
K Xu, S Sun, M Yan, J Cui, Y Yang, W Li… - Frontiers in …, 2022 - frontiersin.org
DEAD-box (DDX) 5 and DDX17, which belong to the DEAD-box RNA helicase family, are
nuclear and cytoplasmic shuttle proteins. These proteins are expressed in most tissues and …
nuclear and cytoplasmic shuttle proteins. These proteins are expressed in most tissues and …
[HTML][HTML] The role of miRNA biogenesis and DDX17 in tumorigenesis and cancer stemness
KJ Wu - biomedical journal, 2020 - Elsevier
Cancer stemness represents one of the major mechanisms that predispose patients to tumor
aggressiveness, metastasis, and treatment resistance. MicroRNA biogenesis is an important …
aggressiveness, metastasis, and treatment resistance. MicroRNA biogenesis is an important …
DDX17 induces epithelial-mesenchymal transition and metastasis through the miR-149-3p/CYBRD1 pathway in colorectal cancer
G Zhao, Q Wang, Y Zhang, R Gu, M Liu, Q Li… - Cell Death & …, 2023 - nature.com
Abstract DEAD box helicase 17 (DDX17) has been reported to be involved in the initiation
and development of several cancers. However, the functional role and mechanisms of …
and development of several cancers. However, the functional role and mechanisms of …
Upregulated miR-9-5p inhibits osteogenic differentiation of bone marrow mesenchymal stem cells under high glucose treatment
C He, M Liu, Q Ding, F Yang, T Xu - Journal of Bone and Mineral …, 2022 - Springer
Introduction Diabetic osteoporosis (DOP) is a chronic diabetic complication, which is
attributed to high glucose (HG)-induced dysfunction of bone marrow mesenchymal stem …
attributed to high glucose (HG)-induced dysfunction of bone marrow mesenchymal stem …
[HTML][HTML] Development and validation of a six-RNA binding proteins prognostic signature and candidate drugs for prostate cancer
L Gao, J Meng, Y Zhang, J Gu, Z Han, X Wang, S Gao - Genomics, 2020 - Elsevier
The dysregulation of RNA binding proteins (RBPs) regulates the progression of several
cancers. However, information on the overall functions of RBPs in prostate cancer (PCa) …
cancers. However, information on the overall functions of RBPs in prostate cancer (PCa) …
RNA-binding proteins and exoribonucleases modulating miRNA in cancer: the enemy within
Y Seo, J Rhim, JH Kim - Experimental & Molecular Medicine, 2024 - nature.com
Recent progress in the investigation of microRNA (miRNA) biogenesis and the miRNA
processing machinery has revealed previously unknown roles of posttranscriptional …
processing machinery has revealed previously unknown roles of posttranscriptional …
[HTML][HTML] KHSRP-bound small nucleolar RNAs associate with promotion of cell invasiveness and metastasis of pancreatic cancer
K Taniuchi, M Ogasawara - Oncotarget, 2020 - ncbi.nlm.nih.gov
KH-type splicing regulatory protein (KHSRP) is an RNA-binding protein implicated in a
variety of cellular processes, including splicing in the nucleus and mRNA localization and …
variety of cellular processes, including splicing in the nucleus and mRNA localization and …
[HTML][HTML] Identification and characterization of known and novel microRNAs in three tissues of Chinese giant salamander base on deep sequencing approach
Y Huang, HT Ren, JL Xiong, XC Gao, XH Sun - Genomics, 2017 - Elsevier
MicroRNAs (miRNAs) are a class of non-coding small RNAs that play important roles in the
regulation of gene expression. Although animal miRNAs have been extensively studied in …
regulation of gene expression. Although animal miRNAs have been extensively studied in …
miR-141 is negatively correlated with TLR4 in neonatal sepsis and regulates LPS-induced inflammatory responses in monocytes
X Lin, Y Wang - Brazilian Journal of Medical and Biological Research, 2021 - SciELO Brasil
Neonatal sepsis is an inflammatory system syndrome and a main cause of neonatal
mortality. However, there is a lack of ideal biomarkers for early neonatal sepsis diagnosis …
mortality. However, there is a lack of ideal biomarkers for early neonatal sepsis diagnosis …