Light as a central modulator of circadian rhythms, sleep and affect
TA LeGates, DC Fernandez, S Hattar - Nature Reviews Neuroscience, 2014 - nature.com
Light has profoundly influenced the evolution of life on earth. As widely appreciated, light
enables us to generate images of our environment. However, light—through intrinsically …
enables us to generate images of our environment. However, light—through intrinsically …
Light and cognition: roles for circadian rhythms, sleep, and arousal
Light exerts a wide range of effects on mammalian physiology and behavior. As well as
synchronizing circadian rhythms to the external environment, light has been shown to …
synchronizing circadian rhythms to the external environment, light has been shown to …
Health consequences of circadian disruption in humans and animal models
JA Evans, AJ Davidson - Progress in molecular biology and translational …, 2013 - Elsevier
Daily rhythms in behavior and physiology are programmed by a hierarchical collection of
biological clocks located throughout the brain and body, known as the circadian system …
biological clocks located throughout the brain and body, known as the circadian system …
Sleep deprivation selectively impairs memory consolidation for contextual fear conditioning
Many behavioral and electrophysiological studies in animals and humans have suggested
that sleep and circadian rhythms influence memory consolidation. In rodents, hippocampus …
that sleep and circadian rhythms influence memory consolidation. In rodents, hippocampus …
Stress, the cortisol awakening response and cognitive function
There is evidence that stress-induced disruption of the circadian rhythm of cortisol secretion,
has negative consequences for brain health. The cortisol awakening response (CAR) is the …
has negative consequences for brain health. The cortisol awakening response (CAR) is the …
Circadian clocks, cognition, and Alzheimer's disease: synaptic mechanisms, signaling effectors, and chronotherapeutics
KR Hoyt, K Obrietan - Molecular neurodegeneration, 2022 - Springer
Modulation of basic biochemical and physiological processes by the circadian timing system
is now recognized as a fundamental feature of all mammalian organ systems. Within the …
is now recognized as a fundamental feature of all mammalian organ systems. Within the …
Circadian rhythms and memory formation
JR Gerstner, JCP Yin - Nature Reviews Neuroscience, 2010 - nature.com
There has been considerable progress in elucidating the molecular mechanisms that
contribute to memory formation and the generation of circadian rhythms. However, it is not …
contribute to memory formation and the generation of circadian rhythms. However, it is not …
Circadian oscillation of hippocampal MAPK activity and cAmp: implications for memory persistence
The mitogen-activated protein kinase (MAPK) and cyclic adenosine monophosphate (cAMP)
signal transduction pathways have critical roles in the consolidation of hippocampus …
signal transduction pathways have critical roles in the consolidation of hippocampus …
Neuroplasticity mediated by altered gene expression
CA McClung, EJ Nestler - Neuropsychopharmacology, 2008 - nature.com
Plasticity in the brain is important for learning and memory, and allows us to respond to
changes in the environment. Furthermore, long periods of stress can lead to structural and …
changes in the environment. Furthermore, long periods of stress can lead to structural and …
The trouble with circadian clock dysfunction: multiple deleterious effects on the brain and body
EL Zelinski, SH Deibel, RJ McDonald - Neuroscience & Biobehavioral …, 2014 - Elsevier
This review consolidates research employing human correlational and experimental work
across brain and body with experimental animal models to provide a more complete …
across brain and body with experimental animal models to provide a more complete …