Wound healing: cellular mechanisms and pathological outcomes

HN Wilkinson, MJ Hardman - Open biology, 2020 - royalsocietypublishing.org
Wound healing is a complex, dynamic process supported by a myriad of cellular events that
must be tightly coordinated to efficiently repair damaged tissue. Derangement in wound …

Methicillin-resistant Staphylococcus aureus (MRSA): antibiotic-resistance and the biofilm phenotype

KM Craft, JM Nguyen, LJ Berg, SD Townsend - MedChemComm, 2019 - pubs.rsc.org
Staphylococcus aureus (S. aureus) is an asymptomatic colonizer of 30% of all human
beings. While generally benign, antibiotic resistance contributes to the success of S. aureus …

Bioactive glasses: a promising therapeutic ion release strategy for enhancing wound healing

T Mehrabi, AS Mesgar… - ACS biomaterials science …, 2020 - ACS Publications
The morbidity, mortality, and burden of burn victims and patients with severe diabetic
wounds are still high, which leads to an extensively growing demand for novel treatments …

[HTML][HTML] Multi-functional silica-based mesoporous materials for simultaneous delivery of biologically active ions and therapeutic biomolecules

H Zhu, K Zheng, AR Boccaccini - Acta Biomaterialia, 2021 - Elsevier
Mesoporous silica-based materials, especially mesoporous bioactive glasses (MBGs), are
being highly considered for biomedical applications, including drug delivery and tissue …

The skin microbiome: current landscape and future opportunities

P Smythe, HN Wilkinson - International journal of molecular sciences, 2023 - mdpi.com
Our skin is the largest organ of the body, serving as an important barrier against the harsh
extrinsic environment. Alongside preventing desiccation, chemical damage and …

“Hard” ceramics for “Soft” tissue engineering: Paradox or opportunity?

S Kargozar, RK Singh, HW Kim, F Baino - Acta Biomaterialia, 2020 - Elsevier
Tissue engineering provides great possibilities to manage tissue damages and injuries in
modern medicine. The involvement of hard biocompatible materials in tissue engineering …

[HTML][HTML] Ag modified mesoporous bioactive glass nanoparticles for enhanced antibacterial activity in 3D infected skin model

K Zheng, P Balasubramanian, TE Paterson… - Materials Science and …, 2019 - Elsevier
Bioactive glasses (BG) are versatile materials for various biomedical applications, including
bone regeneration and wound healing, due to their bone bonding, antibacterial, osteogenic …

[HTML][HTML] Application of metal-based biomaterials in wound repair

H Wang, Z Xu, Q Li, J Wu - Engineered Regeneration, 2021 - Elsevier
Wound repair, as one of the most intricate biological mechanisms, is essential to ensure the
formation and integrity of the skin barrier. However, multiple factors can cause delays and …

[HTML][HTML] Elevated local senescence in diabetic wound healing is linked to pathological repair via CXCR2

HN Wilkinson, C Clowes, KL Banyard… - Journal of Investigative …, 2019 - Elsevier
Cellular senescence can be broadly defined as a stable, but essentially irreversible, loss of
proliferative capacity. Historically, senescence has been described as a negative outcome of …

Bioactive glasses for soft and hard tissue healing applications—A short review

I Negut, C Ristoscu - Applied Sciences, 2023 - mdpi.com
Bioactive glasses have developed into a variety of items that are used in order to treat a
wide range of medical problems. Apart from being mostly applied in the healing processes …