Neuropsychiatric symptoms (NPSs) are common in patients with Alzheimer's disease (AD)
and are associated with accelerated cognitive impairment and earlier deaths. This review …

Background: Affective and emotional symptoms such as depression, anxiety, euphoria, and
irritability are common neuropsychiatric symptoms (NPS) in pre-dementia and cognitively …

Reasons for the Study: The Neuropsychiatric Inventory (NPI) has been used for studies of
neuropsychiatric symptoms in neurodegenerative disorders for the past 25 years. This article …

Agitation is a behavioral syndrome characterized by increased, often undirected, motor
activity, restlessness, aggressiveness, and emotional distress. According to several …

Background Successful development of agents that improve cognition and behavior in
Alzheimer's disease (AD) is critical to improving the lives of patients manifesting the …

Background: The International Psychogeriatric Association (IPA) published a provisional
consensus definition of agitation in cognitive disorders in 2015. As proposed by the original …

Introduction Mild behavioral impairment (MBI) is characterized by later‐life emergence of
neuropsychiatric symptoms. Investigating its relationship with progression to Alzheimer's …

Future research directions include both clinical and basic neuroscience investigations. The
detection of early neuropsychiatric symptoms might be a marker for dementia, and the …

To identify knowledge gaps regarding new‐onset agitation and impulsivity prior to onset of
cognitive impairment or dementia the International Society to Advance Alzheimer's …

Background Neuropsychiatric symptoms (NPS) are frequent in aging and Alzheimer's
disease (AD). Here we study the relationship between NPS and AD pathologies in vivo …