[HTML][HTML] Chikungunya vaccine development, challenges, and pathway toward public health impact

C Maure, K Khazhidinov, H Kang, M Auzenbergs… - Vaccine, 2024 - Elsevier
Chikungunya is a neglected tropical disease of growing public health concern with
outbreaks in more than 114 countries in Asia, Africa, Americas, Europe, and Oceania since …

From bench to clinic: the development of VLA1553/IXCHIQ, a live-attenuated chikungunya vaccine

LH Chen, A Fritzer, R Hochreiter… - Journal of Travel …, 2024 - academic.oup.com
Background Over the past 20 years, over 5 million cases of chikungunya, a mosquito-
transmitted viral disease, have been reported in over 110 countries. Until recently …

[HTML][HTML] Understanding the Transmission Dynamics of the Chikungunya Virus in Africa

Y Ramphal, H Tegally, JE San, ML Reichmuth… - Pathogens, 2024 - mdpi.com
The Chikungunya virus (CHIKV) poses a significant global public health concern, especially
in Africa. Since its first isolation in Tanzania in 1953, CHIKV has caused recurrent outbreaks …

Programmatic considerations and evidence gaps for chikungunya vaccine introduction in countries at risk of chikungunya outbreaks: Stakeholder analysis

M Auzenbergs, C Maure, H Kang, A Clark… - PLoS neglected …, 2024 - journals.plos.org
Chikungunya can have longstanding effects on health and quality of life. Alongside the
recent approval of the world's first chikungunya vaccine by the US Food and Drug …

How mathematical modelling can inform outbreak response vaccination

M Shankar, AM Hartner, CRK Arnold, E Gayawan… - BMC Infectious …, 2024 - Springer
Mathematical models are established tools to assist in outbreak response. They help
characterise complex patterns in disease spread, simulate control options to assist public …

Strategic vaccination responses to Chikungunya outbreaks in Rome: Insights from a dynamic transmission model

AC Sloof, M Boer, GT Vondeling… - PLOS Neglected …, 2024 - journals.plos.org
Background Chikungunya virus (CHIKV) outbreaks, driven by the expanding habitat of the
Aedes albopictus mosquito and global climate change, pose a significant threat to public …

The global health and economic burden of chikungunya from 2011 to 2020: a model-driven analysis on the impact of an emerging vector-borne disease

AM de Roo, GT Vondeling, M Boer, K Murray… - BMJ Global …, 2024 - gh.bmj.com
Introduction Chikungunya is a mosquito-borne arboviral disease posing an emerging global
public health threat. Understanding the global burden of chikungunya is critical for designing …

Determining force of infection for chikungunya to support vaccine policy development

AB Wilder-Smith, A Wilder-Smith - The Lancet Infectious Diseases, 2024 - thelancet.com
Chikungunya is an emerging mosquito-borne viral infection causing an increasing number
of outbreaks in the tropics and subtropics, and smaller outbreaks have also been observed …

Mathematical modelling to inform outbreak response vaccination

M Shankar, AM Hartner, CRK Arnold… - arXiv preprint arXiv …, 2024 - arxiv.org
Mathematical models are established tools to assist in outbreak response. They help
characterise complex patterns in disease spread, simulate control options to assist public …

[HTML][HTML] Correlation Between Pain, Disease Activity, and Rheumatoid Factor Positivity in Patients with Chikungunya Arthritis

JK Amaral, RT Schoen, CO Bingham… - The Yale Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
Chikungunya fever (CHIKF) is an acute viral disease caused by the chikungunya virus
(CHIKV) transmitted by Aedes mosquitoes. The acute phase presents with limited symptoms …