The gastrointestinal (GI) tract plays a central role in the absorption, distribution, metabolism,
and excretion of flavonoids, which ultimately define the health effects of these bioactives …

Polyphenols are abundant micronutrients in our diet, and evidence for their role in the
prevention of degenerative diseases such as cancer and cardiovascular diseases is …

Polyphenols and consequently many flavonoids have several beneficial actions on human
health. However, the actual molecular interactions of polyphenols with biological systems …

Many of the potential health benefits of flavonoids have been associated with their specific
chemical and biological properties including their ability to interact and bind non-covalently …

Abstract as a consequence of industrial development, the environment is increasingly
polluted with heavy metals. Plants possess homeostatic mechanisms that allow them to …

Accumulating chemical, biochemical, clinical and epidemiological evidence supports the
chemoprotective effects of phenolic antioxidants against oxidative stress-mediated …

Type 2 diabetes mellitus (T2DM) is a complex metabolic disorder with various contributing
factors including genetics, epigenetics, environment and lifestyle such as diet. The hallmarks …

Main conclusion This review summarizes the anti-stress effects of flavonoids in plants and
highlights its role in the regulation of polar auxin transport and free radical scavenging …

Numerous studies indicate that moderate red wine consumption is associated with a
protective effect against all-cause mortality. Since oxidative stress constitutes a unifying …

Flavonoids can exert beneficial health effects through multiple mechanisms. In this paper,
we address the important, although not fully understood, capacity of flavonoids to interact …