Peptides have positively impacted the pharmaceutical industry as drugs, biomarkers, or
diagnostic tools of high therapeutic value. However, only a handful have progressed to the …

Nature's way for bioactive peptides is to provide them with several related functions and the
ability to cooperate in performing their job. Natural cell-penetrating peptides (CPP), such as …

An infecting and propagating parasite relies on its innate defense system to evade the host's
immune response and to survive challenges from commensal bacteria. More so for the …

Scorpion venoms have proven to be excellent sources of antimicrobial agents. However,
although many of them have been functionally characterized, they remain underutilized as …

Introduction: Low-molecular-weight antibiotics are gradually rendered ineffective by
multidrug-resistant bacteria. Promising replacements are fast-acting antimicrobial peptides …

Antimicrobial peptides (AMPs) can be directed to specific membranes based on differences
in lipid composition. In this study, we performed atomistic and coarse-grained simulations of …

Anticancer lipopeptides (ACLPs) are considered promising alternatives to combat resistant
cancer cells, but the influence of peptide conformational propensity alone on their selectivity …

Kiadins are in silico designed peptides with a strong similarity to di PGLa-H, a tandem
sequence of PGLa-H (KIAKVALKAL) and with single, double or quadruple glycine …

Bioenergetics deals with the very first energy transformation steps performed by living cells.
Increased dissipation is the primary effect of processing external energy packages. Enzyme …

Adepantins are peptides designed to optimize antimicrobial biological activity through the
choice of specific amino acid residues, resulting in helical and amphipathic structures. This …