Aging is a major cause of many degenerative diseases. The most intuitive consequence of
aging is mainly manifested on the skin, resulting in cumulative changes in skin structure …

The skin is the largest organ and has a key protective role. Similar to any other tissue, the
skin is influenced not only by intrinsic/chronological aging, but also by extrinsic aging …

Protein homeostasis is a vital process for cell function and, therefore, disruption of the
molecular mechanisms involved in this process, such as autophagy, may contribute to …

Cellular senescence and aging result in a reduced ability to manage persistent types of
inflammation. Thus, the chronic low-level inflammation associated with aging phenotype is …

Nowadays, caffeine is one of the most commonly consumed substances, which presents in
many plants and products. It has both positive and negative effects on the human body, and …

The marked augment of drug-resistance to traditional antibiotics underlines the crying need
for novel replaceable antibacterials. Research advances have revealed the considerable …

Parkinson's disease (PD) is the second most common neurodegenerative disorder,
characterized by dopaminergic neurodegeneration, motor impairment and non-motor …

Despite the growing interest by researchers into cellular senescence, a hallmark of cellular
aging, its role in human skin remains equivocal. The skin is the largest and most accessible …

Excessive inflammation induced by various risk factors is associated with the development
of bronchopulmonary dysplasia (BPD). Caffeine exerts potent anti-inflammatory effects as a …

Low back pain (LBP) is a leading cause of labour loss and disability worldwide, and it also
imposes a severe economic burden on patients and society. Among symptomatic LBP …