[HTML][HTML] Antimicrobial peptides: interaction with model and biological membranes and synergism with chemical antibiotics

A Hollmann, M Martinez, P Maturana… - Frontiers in …, 2018 - frontiersin.org
Antimicrobial peptides (AMPs) are promising novel antibiotics since they have shown
antimicrobial activity against a wide range of bacterial species, including multiresistant …

Fluorescent analogs of biomolecular building blocks: design, properties, and applications

RW Sinkeldam, NJ Greco, Y Tor - Chemical reviews, 2010 - ACS Publications
Fluorescence spectroscopy, one of the most informative and sensitive analytical techniques,
has played and continues to play key roles in modern research. Indeed, unraveling the inner …

Antimicrobial peptides: linking partition, activity and high membrane-bound concentrations

MN Melo, R Ferre, MARB Castanho - Nature Reviews Microbiology, 2009 - nature.com
An increasing amount of information on the action of antimicrobial peptides (AMPs) at the
molecular level has not yet been translated into a comprehensive understanding of effects in …

[HTML][HTML] Fluorescence probe partitioning between Lo/Ld phases in lipid membranes

T Baumgart, G Hunt, ER Farkas, WW Webb… - … et Biophysica Acta (BBA …, 2007 - Elsevier
Fluorescence microscopy imaging is an important technique for studying lipid membranes
and is increasingly being used for examining lipid bilayer membranes, especially those …

Role of amphipathicity and hydrophobicity in the balance between hemolysis and peptide–membrane interactions of three related antimicrobial peptides

A Hollmann, M Martínez, ME Noguera… - Colloids and Surfaces B …, 2016 - Elsevier
Cationic antimicrobial peptides (CAMPs) represent important self defense molecules in
many organisms, including humans. These peptides have a broad spectrum of activities …

[HTML][HTML] Design and characterization of novel antimicrobial peptides, R-BP100 and RW-BP100, with activity against Gram-negative and Gram-positive bacteria

IM Torcato, YH Huang, HG Franquelim… - … et Biophysica Acta (BBA …, 2013 - Elsevier
BP100 is a short cationic antimicrobial peptide with a mechanism of action dependent on
peptide–lipid interactions and microbial surface charge neutralization. Although active …

Liposomes as biomembrane models: Biophysical techniques for drug-membrane interaction studies

S Andrade, MJ Ramalho, JA Loureiro… - Journal of molecular …, 2021 - Elsevier
The interaction of drugs with biological membranes is a critical factor affecting their
pharmacokinetics and pharmacodynamics, so understanding how drugs interact with …

[HTML][HTML] Analysis of the equilibrium distribution of ligands in heterogeneous media–Approaches and pitfalls

MJ Moreno, LMS Loura, J Martins, A Salvador… - International Journal of …, 2022 - mdpi.com
The equilibrium distribution of small molecules (ligands) between binding agents in
heterogeneous media is an important property that determines their activity. Heterogeneous …

Phase diagrams of lipid mixtures relevant to the study of membrane rafts

FM Goñi, A Alonso, LA Bagatolli, RE Brown… - … et Biophysica Acta (BBA …, 2008 - Elsevier
The present paper reviews the phase properties of phosphatidylcholine–sphingomyelin–
cholesterol mixtures, that are often used as models for membrane “raft” microdomains. The …

[HTML][HTML] The role of tryptophans on the cellular uptake and membrane interaction of arginine-rich cell penetrating peptides

ML Jobin, M Blanchet, S Henry, S Chaignepain… - … et Biophysica Acta (BBA …, 2015 - Elsevier
Cell-penetrating peptides (CPP) are able to efficiently transport cargos across cell
membranes without being cytotoxic to cells, thus present a great potential in drug delivery …