Background Precision and personalized nutrition approaches aim to leverage human
variability to design tailored dietary interventions to improve health. With an extensive range …

Precision nutrition is an emerging area of nutrition research, with primary focus on the
individual variability in response to dietary and lifestyle factors, which are mainly determined …

Context Carnitine palmitoyltransferase-1A, encoded by the CPT1A gene, plays a key role in
the oxidation of long-chain fatty acids in the mitochondria and may be important in …

Precision nutrition has emerged as a boiling area of nutrition research, with a particular
focus on revealing the individual variability in response to diets that is determined mainly by …

The POUNDS Lost trial is a 2-year clinical trial testing the effects of dietary interventions on
weight loss. This study included 811 adults with overweight or obesity who were randomized …

Over the past 50 years, the number of overweight/obese people increased significantly,
making obesity a global public health challenge. Apart from rare monogenic forms, obesity is …

Background: DNA methylation (DNAm) may play a critical role in bridging prenatal adverse
events and cardiometabolic disorders including hypertension in later life. Methods: We …

Obesity is a complex multifactorial condition that often manifests in early life with a lifelong
burden on metabolic health. Diet, including pre-pregnancy maternal diet, in utero nutrition …

The overall aim of precision nutrition is to replace the 'one size fits all'approach to dietary
advice with recommendations that are more specific to the individual in order to improve the …

Summary Background Type 2 diabetes (T2D) susceptibility is influenced by genetic and
environmental factors. Previous findings suggest DNA methylation as a potential mechanism …