Molecular mechanisms of cognitive dysfunction following traumatic brain injury

KR Walker, G Tesco - Frontiers in aging neuroscience, 2013 - frontiersin.org
Traumatic brain injury (TBI) results in significant disability due to cognitive deficits
particularly in attention, learning and memory, and higher-order executive functions. The …

The potential for animal models to provide insight into mild traumatic brain injury: translational challenges and strategies

SR Shultz, SJ McDonald, CV Haar, A Meconi… - Neuroscience & …, 2017 - Elsevier
Mild traumatic brain injury (mTBI) is a common health problem. There is tremendous
variability and heterogeneity in human mTBI, including mechanisms of injury, biomechanical …

A national study on the effects of concussion in collegiate athletes and US military service academy members: the NCAA–DoD concussion assessment, research and …

SP Broglio, M McCrea, T McAllister, J Harezlak, B Katz… - Sports medicine, 2017 - Springer
Background The natural history of mild traumatic brain injury (TBI) or concussion remains
poorly defined and no objective biomarker of physiological recovery exists for clinical use …

Acute CSF interleukin-6 trajectories after TBI: associations with neuroinflammation, polytrauma, and outcome

RG Kumar, ML Diamond, JA Boles, RP Berger… - Brain, behavior, and …, 2015 - Elsevier
Traumatic brain injury (TBI) results in a significant inflammatory burden that perpetuates the
production of inflammatory mediators and biomarkers. Interleukin-6 (IL-6) is a pro …

[HTML][HTML] Genetic influences in traumatic brain injury

ER Bennett, K Reuter-Rice, DT Laskowitz - 2015 - europepmc.org
Traumatic brain injury (TBI) is a leading cause of death and disability worldwide, affecting all
ages and demographics. In the United States alone, approximately 1.7 million new cases …

Impact of traumatic brain injury on dopaminergic transmission

YH Chen, EYK Huang, TT Kuo, J Miller… - Cell …, 2017 - journals.sagepub.com
Brain trauma is often associated with severe morbidity and is a major public health concern.
Even when injury is mild and no obvious anatomic disruption is seen, many individuals …

Intracranial pressure trajectories: a novel approach to informing severe traumatic brain injury phenotypes

RM Jha, J Elmer, BE Zusman, S Desai… - Critical care …, 2018 - journals.lww.com
Objectives: Intracranial pressure in traumatic brain injury is dynamic and influenced by
factors like injury patterns, treatments, and genetics. Existing studies use time invariant …

[图书][B] Neurobiology of brain disorders: biological basis of neurological and psychiatric disorders

MJ Zigmond, CA Wiley, MF Chesselet - 2022 - books.google.com
Neurobiology of Brain Disorders: Biological Basis of Neurological and Psychiatric Disorders,
Second Edition provides basic scientists a comprehensive overview of neurological and …

Systematic review of genetic risk factors for sustaining a mild traumatic brain injury

WJ Panenka, AJ Gardner, MN Dretsch… - Journal of …, 2017 - liebertpub.com
This systematic review examined the association between genetics and risk for sustaining a
traumatic brain injury. We retrieved articles published in English from 1980 to July 2016 …

White and gray matter contributions to executive function recovery after traumatic brain injury

I Cristofori, W Zhong, A Chau, J Solomon, F Krueger… - Neurology, 2015 - AAN Enterprises
Objective: We investigated the association between regional white and gray matter volume
loss and performance on executive functions (EFs) in patients with penetrating traumatic …