Insulin-like growth factor-2 (IGF-2) in fibrosis
Y Zhu, L Chen, B Song, Z Cui, G Chen, Z Yu, B Song - Biomolecules, 2022 - mdpi.com
The insulin family consists of insulin, insulin-like growth factor 1 (IGF-1), insulin-like growth
factor 2 (IGF-2), their receptors (IR, IGF-1R and IGF-2R), and their binding proteins. All three …
factor 2 (IGF-2), their receptors (IR, IGF-1R and IGF-2R), and their binding proteins. All three …
[HTML][HTML] Biomarkers Identification in the Microenvironment of Oral Squamous Cell Carcinoma: A Systematic Review of Proteomic Studies
An important determinant for oral squamous cell carcinoma (OSCC) onset and outcome is
the composition of the tumor microenvironment (TME). Thus, the study of the interactions …
the composition of the tumor microenvironment (TME). Thus, the study of the interactions …
Tracing the dynamics of gene transcripts after organismal death
AE Pozhitkov, R Neme, T Domazet-Lošo… - Open …, 2017 - royalsocietypublishing.org
In life, genetic and epigenetic networks precisely coordinate the expression of genes—but in
death, it is not known if gene expression diminishes gradually or abruptly stops or if specific …
death, it is not known if gene expression diminishes gradually or abruptly stops or if specific …
Cathepsins trigger cell death and regulate radioresistance in glioblastoma
X Ding, C Zhang, H Chen, M Ren, X Liu - Cells, 2022 - mdpi.com
Treatment of glioblastoma (GBM) remains very challenging, and it is particularly important to
find sensitive and specific molecular targets. In this work, we reveal the relationship between …
find sensitive and specific molecular targets. In this work, we reveal the relationship between …
[PDF][PDF] RETRACTED: NFIL3 Facilitates Neutrophil Autophagy, Neutrophil Extracellular Trap Formation and Inflammation During Gout via REDD1-Dependent mTOR …
H Tang, C Tan, X Cao, Y Liu, H Zhao, Y Liu… - Frontiers in …, 2021 - frontiersin.org
Autophagy pathways play an important role in immunity and inflammation via pathogen
clearance mechanisms mediated by immune cells, such as macrophages and neutrophils …
clearance mechanisms mediated by immune cells, such as macrophages and neutrophils …
Fisetin attenuates doxorubicin‐induced cardiotoxicity by inhibiting the insulin‐like growth factor II receptor apoptotic pathway through estrogen receptor‐α/‐β activation
Doxorubicin (DOX), an effective chemotherapeutic drug, has been used to treat various
cancers; however, its cardiotoxic side effects restrict its therapeutic efficacy. Fisetin, a …
cancers; however, its cardiotoxic side effects restrict its therapeutic efficacy. Fisetin, a …
miR‐203 accelerates apoptosis and inflammation induced by LPS via targeting NFIL3 in cardiomyocytes
Y Li, X Liu, A Du, X Zhu, B Yu - Journal of cellular biochemistry, 2019 - Wiley Online Library
Myocarditis is an inflammatory disease of the myocardium. MicroRNA‐203 (miR‐203) is
involved in various physiological and pathological processes. In this work, we aimed to …
involved in various physiological and pathological processes. In this work, we aimed to …
A Potential Role of NFIL3 in Atherosclerosis
GG Zeng, J Zhou, WL Jiang, J Yu, GY Nie, J Li… - Current problems in …, 2024 - Elsevier
Abstract Nuclear factor interleukin-3 (NFIL3), a proline-and acidic-residue-rich (PAR) bZIP
transcription factor, is called the E4 binding protein 4 (E4BP4) as well, which is relevant to …
transcription factor, is called the E4 binding protein 4 (E4BP4) as well, which is relevant to …
Estrogen and/or estrogen receptor α inhibits BNIP3-induced apoptosis and autophagy in H9c2 cardiomyoblast cells
BC Chen, YJ Weng, MA Shibu, CK Han… - International Journal of …, 2018 - mdpi.com
The process of autophagy in heart cells maintains homeostasis during cellular stress such
as hypoxia by removing aggregated proteins and damaged organelles and thereby protects …
as hypoxia by removing aggregated proteins and damaged organelles and thereby protects …
Anthocyanin attenuates doxorubicin-induced cardiomyotoxicity via estrogen receptor-α/β and stabilizes HSF1 to inhibit the IGF-IIR apoptotic pathway
Doxorubicin (Dox) is extensively used for chemotherapy in different types of cancer, but its
use is limited to because of its cardiotoxicity. Our previous studies found that doxorubicin …
use is limited to because of its cardiotoxicity. Our previous studies found that doxorubicin …