Thyroid carcinoma: phenotypic features, underlying biology and potential relevance for targeting therapy
J Hu, IJ Yuan, S Mirshahidi, A Simental, SC Lee… - International journal of …, 2021 - mdpi.com
Thyroid carcinoma consists a group of phenotypically heterogeneous cancers. Recent
advances in biological technologies have been advancing the delineation of genetic …
advances in biological technologies have been advancing the delineation of genetic …
Epithelial-to-mesenchymal transition in thyroid cancer: a comprehensive review
H Shakib, S Rajabi, MH Dehghan, FJ Mashayekhi… - Endocrine, 2019 - Springer
The Metastatic progression of solid tumors, such as thyroid cancer is a complex process
which involves various factors. Current understanding on the role of epithelial …
which involves various factors. Current understanding on the role of epithelial …
Fibronectin-1 expression is increased in aggressive thyroid cancer and favors the migration and invasion of cancer cells
M Sponziello, F Rosignolo, M Celano… - Molecular and cellular …, 2016 - Elsevier
In this study we analyzed the expression levels of markers of epithelial-to-mesenchymal
transition (EMT) in several papillary thyroid carcinomas (PTCs) and the relation with tumor …
transition (EMT) in several papillary thyroid carcinomas (PTCs) and the relation with tumor …
Curcumin inhibits metastasis in human papillary thyroid carcinoma BCPAP cells via down-regulation of the TGF-β/Smad2/3 signaling pathway
L Zhang, X Cheng, Y Gao, C Zhang, J Bao… - Experimental cell …, 2016 - Elsevier
Thyroid cancers usually possess a good prognosis while the risks of recurrence and
metastasis turn out to be a disturbing issue. Curcumin [bis (4-hydroxy-3-methoxy-phenyl)-1 …
metastasis turn out to be a disturbing issue. Curcumin [bis (4-hydroxy-3-methoxy-phenyl)-1 …
[HTML][HTML] MGRN1 depletion promotes intercellular adhesion in melanoma by upregulation of E-cadherin and inhibition of CDC42
S Cerdido, M Abrisqueta, J Sánchez-Beltrán… - Cancer Letters, 2024 - Elsevier
Abstract Mahogunin Ring Finger 1 is an E3-ubiquitin ligase encoded by the color gene
MGRN1. Our previous in vitro and in vivo studies demonstrated that Mgrn1 deletion in …
MGRN1. Our previous in vitro and in vivo studies demonstrated that Mgrn1 deletion in …
The role of exosomes in epithelial–to-mesenchymal transition and cell functional properties in head and neck cancer
NS Mastronikolis, E Kyrodimos, D Spyropoulou… - Cancers, 2023 - mdpi.com
Simple Summary According to WHO 2018 estimates, cancer is the second leading cause of
mortality worldwide after cardiovascular disease, accounting for one in six fatalities. Mortality …
mortality worldwide after cardiovascular disease, accounting for one in six fatalities. Mortality …
Oncogenic BRAF disrupts thyroid morphogenesis and function via twist expression
V Anelli, JA Villefranc, S Chhangawala… - elife, 2017 - elifesciences.org
Thyroid cancer is common, yet the sequence of alterations that promote tumor formation are
incompletely understood. Here, we describe a novel model of thyroid carcinoma in zebrafish …
incompletely understood. Here, we describe a novel model of thyroid carcinoma in zebrafish …
Role of GLI2 in hypopituitarism phenotype
IJP Arnhold, MM França, LR Carvalho… - Journal of …, 2015 - jme.bioscientifica.com
GLI2 is a zinc-finger transcription factor involved in the Sonic Hedgehog pathway. Gli2
mutant mice have hypoplastic anterior and absent posterior pituitary glands. We reviewed …
mutant mice have hypoplastic anterior and absent posterior pituitary glands. We reviewed …
Downregulation of Snail by DUSP1 impairs cell migration and invasion through the inactivation of JNK and ERK and is useful as a predictive factor in the prognosis of …
D Martínez-Martínez, MV Toledo Lobo, P Baquero… - Cancers, 2021 - mdpi.com
Simple Summary The role of dual specificity phosphatase 1 (DUSP1) in metastasis-
associated processes in prostate cancer and its impact on patient outcome remains to be …
associated processes in prostate cancer and its impact on patient outcome remains to be …
[HTML][HTML] Protein kinase D activity is a risk biomarker in prostate cancer that drives cell invasion by a Snail/ERK dependent mechanism
D Cilleros-Rodríguez, MV Toledo-Lobo… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Protein kinase D (PKD) family members play controversial roles in prostate cancer (PC).
Thus, PKD1 is nearly absent in advanced tumours, where PKD2 and PKD3 are upregulated …
Thus, PKD1 is nearly absent in advanced tumours, where PKD2 and PKD3 are upregulated …