Synthetic microbial communities (SynComs) of the human gut: design, assembly, and applications
The human gut harbors native microbial communities, forming a highly complex ecosystem.
Synthetic microbial communities (SynComs) of the human gut are an assembly of …
Synthetic microbial communities (SynComs) of the human gut are an assembly of …
[HTML][HTML] Moving beyond descriptive studies: harnessing metabolomics to elucidate the molecular mechanisms underpinning host-microbiome phenotypes
Advances in technology and software have radically expanded the scope of metabolomics
studies and allow us to monitor a broad transect of central carbon metabolism in routine …
studies and allow us to monitor a broad transect of central carbon metabolism in routine …
Dynamic metabolic interactions and trophic roles of human gut microbes identified using a minimal microbiome exhibiting ecological properties
SA Shetty, I Kostopoulos, SY Geerlings… - The ISME …, 2022 - academic.oup.com
Microbe–microbe interactions in the human gut are influenced by host-derived glycans and
diet. The high complexity of the gut microbiome poses a major challenge for unraveling the …
diet. The high complexity of the gut microbiome poses a major challenge for unraveling the …
A bacterial sialidase mediates early-life colonization by a pioneering gut commensal
The early microbial colonization of the gastrointestinal tract can have long-term impacts on
development and health. Keystone species, including Bacteroides spp., are prominent in …
development and health. Keystone species, including Bacteroides spp., are prominent in …
Impact of bacteriocin-producing strains on bacterial community composition in a simplified human intestinal microbiota
NS Ríos Colombo, M Perez-Ibarreche… - Frontiers in …, 2023 - frontiersin.org
Bacteriocins are antimicrobial peptides that have been studied for decades as food bio-
preservatives or as alternatives to antibiotics. They also have potential as modulators of the …
preservatives or as alternatives to antibiotics. They also have potential as modulators of the …
Microbiota-directed biotherapeutics: Considerations for quality and functional assessment
Mounting evidence points to causative or correlative roles of gut microbiome in the
development of a myriad of diseases ranging from gastrointestinal diseases, metabolic …
development of a myriad of diseases ranging from gastrointestinal diseases, metabolic …
[HTML][HTML] MAIT cell activation is reduced by direct and microbiota-mediated exposure to bisphenols
JL Krause, B Engelmann, UN Da Rocha… - Environment …, 2022 - Elsevier
Oral uptake is the primary route of human bisphenol exposure, resulting in an exposure of
the intestinal microbiota and intestine-associated immune cells. Therefore, we compared the …
the intestinal microbiota and intestine-associated immune cells. Therefore, we compared the …
Designs and methodologies to recreate in vitro human gut microbiota models
F Biagini, C Daddi, M Calvigioni, C De Maria… - Bio-Design and …, 2023 - Springer
The human gut microbiota is widely considered to be a metabolic organ hidden within our
bodies, playing a crucial role in the host's physiology. Several factors affect its composition …
bodies, playing a crucial role in the host's physiology. Several factors affect its composition …
[HTML][HTML] The glyphosate formulation Roundup® LB plus influences the global metabolome of pig gut microbiota in vitro
Glyphosate is the world's most widely used herbicide, and its potential side effects on the
intestinal microbiota of various animals, from honeybees to livestock and humans, are …
intestinal microbiota of various animals, from honeybees to livestock and humans, are …
In vitro and in vivo models for evaluating the oral toxicity of nanomedicines
S Lama, O Merlin-Zhang, C Yang - Nanomaterials, 2020 - mdpi.com
Toxicity studies for conventional oral drug formulations are standardized and well
documented, as required by the guidelines of administrative agencies such as the US Food …
documented, as required by the guidelines of administrative agencies such as the US Food …