Interleukin-6 signaling pathway in targeted therapy for cancer

Y Guo, F Xu, TJ Lu, Z Duan, Z Zhang - Cancer treatment reviews, 2012 - Elsevier
Interleukin-6 (IL-6) is a multifunctional cytokine which plays an important role in a wide
range of biologic activities in different types of cell including tumor cells. IL-6 is involved in …

Exercise training, circulating cytokine levels and immune function in cancer survivors: a meta-analysis

N Khosravi, L Stoner, V Farajivafa… - Brain, behavior, and …, 2019 - Elsevier
Background Anti-cancer therapies lead to chronic non-resolving inflammation and reduced
immune function. One potential therapy is exercise training, but the effectiveness of these …

Role of systemic inflammatory response in predicting survival in patients with primary operable cancer

CSD Roxburgh, DC McMillan - Future oncology, 2010 - Taylor & Francis
Disease progression in cancer is dependent on the complex interaction between the tumor
and the host inflammatory response. There is substantial evidence in advanced cancer that …

C-reactive protein is an important biomarker for prognosis tumor recurrence and treatment response in adult solid tumors: a systematic review

S Shrotriya, D Walsh, N Bennani-Baiti, S Thomas… - PloS one, 2015 - journals.plos.org
Purpose A systematic literature review was done to determine the relationship between
elevated CRP and prognosis in people with solid tumors. C-reactive protein (CRP) is a …

Progress in understanding the IL-6/STAT3 pathway in colorectal cancer

Y Lin, Z He, J Ye, Z Liu, X She, X Gao… - OncoTargets and …, 2020 - Taylor & Francis
As a pleiotropic cytokine, interleukin-6 (IL-6) not only regulates the cellular immune
response, but it also promotes tumor development by activating multiple carcinogenic …

Cytokine patterns in cancer patients: A review of the correlation between interleukin 6 and prognosis

BE Lippitz, RA Harris - Oncoimmunology, 2016 - Taylor & Francis
Objective: In tumor patients, IL-6 appears to be one component of a consistent cancer-
associated cytokine network resulting in both a systemic immune stimulation and a …

An inflammation-based prognostic score and its role in the nutrition-based management of patients with cancer: Nutrition Society and BAPEN Medical Symposium on ' …

DC McMillan - Proceedings of the Nutrition Society, 2008 - cambridge.org
Progressive involuntary weight loss, in particular the loss of lean tissue, is common in
patients with advanced cancer and has long been recognised to result in a deterioration in …

[HTML][HTML] Systematic literature review of IL-6 as a biomarker or treatment target in patients with gastric, bile duct, pancreatic and colorectal cancer

N Vainer, C Dehlendorff, JS Johansen - Oncotarget, 2018 - ncbi.nlm.nih.gov
Gastrointestinal cancer (GI) is a major health problem. Patients with gastric, pancreatic,
colorectal, bile duct and gall bladder cancer often have advanced disease at the time of …

A systematic review of the association between circulating concentrations of C reactive protein and cancer

K Heikkilä, S Ebrahim, DA Lawlor - Journal of Epidemiology & …, 2007 - jech.bmj.com
The objective of this study was to review and summarise the published evidence for an
association between circulating concentrations of C reactive protein (CRP) and cancer …

Serum interleukin-6 levels in colorectal cancer patients—a summary of published results

H Knüpfer, R Preiss - International journal of colorectal disease, 2010 - Springer
Introduction It is now clear that inflammation and cancer initiation and progression are
linked. Interleukin-6 (IL-6) is a pleiotropic inflammatory cytokine with described cancer …