Melatonin: a mitochondrial targeting molecule involving mitochondrial protection and dynamics
Melatonin has been speculated to be mainly synthesized by mitochondria. This speculation
is supported by the recent discovery that aralkylamine N-acetyltransferase/serotonin N …
is supported by the recent discovery that aralkylamine N-acetyltransferase/serotonin N …
Ischemic stroke and mitochondria: mechanisms and targets
Stroke is one of the main causes of mortality and disability in most countries of the world.
The only way of managing patients with ischemic stroke is the use of intravenous tissue …
The only way of managing patients with ischemic stroke is the use of intravenous tissue …
Advances in stroke pharmacology
Z Zhou, J Lu, WW Liu, A Manaenko, X Hou… - Pharmacology & …, 2018 - Elsevier
Stroke occurs when a cerebral blood vessel is blocked or ruptured, and it is the major cause
of death and adult disability worldwide. Various pharmacological agents have been …
of death and adult disability worldwide. Various pharmacological agents have been …
Ischemic stroke, obesity, and the anti‐inflammatory role of melatonin
N Yawoot, P Govitrapong, C Tocharus, J Tocharus - Biofactors, 2021 - Wiley Online Library
Obesity is a predominant risk factor in ischemic stroke and is commonly comorbid with it.
Pathologies following these conditions are associated with systemic and local inflammation …
Pathologies following these conditions are associated with systemic and local inflammation …
Effects of organochlorine pesticide residues in maternal body on infants
SY Qi, XL Xu, WZ Ma, SL Deng, ZX Lian… - Frontiers in …, 2022 - frontiersin.org
There are many organochlorine pollutants in the environment, which can be directly or
indirectly exposed to by mothers, and as estrogen endocrine disruptors can cause damage …
indirectly exposed to by mothers, and as estrogen endocrine disruptors can cause damage …
Melatonin regulates microglial polarization and protects against ischemic stroke-induced brain injury in mice
D Li, T He, Y Zhang, J Liu, H Zhao, D Wang… - Experimental …, 2023 - Elsevier
Ischemic stroke is a leading cause of mortality and morbidity worldwide, with
neuroinflammation playing a key role in its pathophysiology. Microglia, the primary immune …
neuroinflammation playing a key role in its pathophysiology. Microglia, the primary immune …
Ischemic brain injury: New insights on the protective role of melatonin
Stroke represents one of the most common causes of brain's vulnerability for many millions
of people worldwide. The plethora of physiopathological events associated with brain …
of people worldwide. The plethora of physiopathological events associated with brain …
[HTML][HTML] Beyond the brain: the systemic pathophysiological response to acute ischemic stroke
Stroke research has traditionally focused on the cerebral processes following ischemic brain
injury, where oxygen and glucose deprivation incite prolonged activation of excitatory …
injury, where oxygen and glucose deprivation incite prolonged activation of excitatory …
Increased oxidative stress markers in acute ischemic stroke patients treated with thrombolytics
H Pawluk, R Kołodziejska, G Grześk… - International Journal of …, 2022 - mdpi.com
One of the most common neurological disorders involving oxidative stress is stroke. During a
stroke, the balance of redox potential in the cell is disturbed, and, consequently, protein …
stroke, the balance of redox potential in the cell is disturbed, and, consequently, protein …
Emerging role of PARP‐1 and PARthanatos in ischemic stroke
Cell death is a key feature of neurological diseases, including stroke and neurodegenerative
disorders. Studies in a variety of ischemic/hypoxic mouse models demonstrate that poly …
disorders. Studies in a variety of ischemic/hypoxic mouse models demonstrate that poly …