A strong cohort of evidence exists that supports the localisation of corneal stem cells at the
limbus. The distinguishing characteristics of limbal cells as stem cells include slow cycling …

Current efforts in structural biology aim to integrate structural information within the context of
cellular organization and function. X-rays and infrared radiation stand at opposite ends of …

We present imaging of corneal pathologies using optical coherence tomography (OCT) with
high resolution. To this end, an ultrahigh-resolution spectral domain OCT (UHR-OCT) …

Infrared spectroscopy and microscopy have heralded a period of rapid advances in tissue
and cellular characterization during the past decade. However, vibrational spectroscopy is …

Screening exfoliative cytology for early dysplastic cells reduces incidence and mortality from
squamous carcinoma of the cervix. In the developed world, screening programmes have …

We propose, here, an FT-IR method to monitor the spontaneous differentiation of murine
embryonic stem (ES) cells in their early development. Principal component analysis and …

There is a requirement for a noninvasive technique to monitor stem cell differentiation.
Several candidates based on optical spectroscopy are discussed in this review: Fourier …

Complex biomolecules absorb in the mid-infrared (λ= 2–20 μm), giving vibrational spectra
associated with structure and function. We used Fourier transform infrared (FTIR) …

Raman and infrared (IR) spectroscopy are two complementary vibrational spectroscopic
techniques that have experienced a tremendous growth in their use in biological and …

Over the last few years, there has been an increased interest in the study of stem cells in
biomedicine for therapeutic use and as a source for healing diseased or injured …