Background Oxidative stress and inflammation contribute to the etiopathogenesis of several
human chronic diseases, such as cancer, diabetes, cardiovascular diseases and metabolic …

Berries are considered “promising functional fruits” due to their distinct and ubiquitous
therapeutic contents of anthocyanins, proanthocyanidins, phenolic acids, flavonoids …

Cadmium is an extremely dangerous heavy metal that can lead to disastrous consequences
in all organisms. Several natural remedies reduce the toxicities of experimentally generated …

Growing evidence suggests that a high fat diet (HFD) induces oxidative stress on the central
nervous system (CNS), which predisposes to mood disorders and neuroinflammation. In this …

Neuroinflammation is a trigger for several neurodegenerative and neuropsychiatric
disorders. Exposure to noxious external stimuli induces homeostatic disturbances resulting …

The influence of gut microbiota in the onset and development of several metabolic diseases
has gained attention over the last few years. Diet plays an essential role in gut microbiota …

Objectives Common mental disorders (CMD) are associated with impaired frontal
excitatory/inhibitory (E/I) balance and reduced grey matter volume (GMV). Larger GMV (in …

In addition to the known metabolic alterations, obesity has consequences at the brain level,
driving imbalance in neurotransmitters such as glutamate (Glu), glutamine (Gln), and …

Dopamine is an important neuromodulator in the brain that binds to dopamine D1-like
receptors (D1, D5) as well as dopamine D2-like receptors (D2, D3, D4). The D2 receptor is …

Introduction: Hypercaloric diets induce oxidative stress, and consequently induce
hyperglycemia and type 2 diabetes mellitus (T2DM). Thus, oxidative stress is significantly …