Weight loss strategies for treatment of obesity: lifestyle management and pharmacotherapy

RF Kushner - Progress in cardiovascular diseases, 2018 - Elsevier
Obesity is one of the most serious and prevalent non-communicable diseases of the twenty-
first century. It is also a patient-centered condition in which affected individuals seek …

Food addiction and binge eating: lessons learned from animal models

MG Novelle, C Diéguez - Nutrients, 2018 - mdpi.com
The feeding process is required for basic life, influenced by environment cues and tightly
regulated according to demands of the internal milieu by regulatory brain circuits. Although …

The steroid hormone 20-hydroxyecdysone binds to dopamine receptor to repress lepidopteran insect feeding and promote pupation

XL Kang, JY Zhang, D Wang, YM Zhao, XL Han… - PLoS …, 2019 - journals.plos.org
Holometabolous insects stop feeding at the final larval instar stage and then undergo
metamorphosis; however, the mechanism is unclear. In the present study, using the serious …

Lorcaserin: A review of its preclinical and clinical pharmacology and therapeutic potential

GA Higgins, PJ Fletcher, WR Shanahan - Pharmacology & Therapeutics, 2020 - Elsevier
The selective 5-HT2C receptor agonist lorcaserin, in conjunction with lifestyle modification,
was approved by the FDA in 2012 for weight management. It has been marketed in the US …

Striatal dopamine D2-like receptors availability in obesity and its modulation by bariatric surgery: A systematic review and meta-analysis

G Ribeiro, A Maia, G Cotovio, FPM Oliveira… - Scientific Reports, 2023 - nature.com
There is significant evidence linking a 'reward deficiency syndrome'(RDS), comprising
decreased availability of striatal dopamine D2-like receptors (DD2lR) and addiction-like …

Off-label drugs for weight management

EJ Hendricks - Diabetes, metabolic syndrome and obesity: targets …, 2017 - Taylor & Francis
The global pandemic of obesity and overweight now affects between 2.8 and 3.5 billion of
the world population and shows no signs of abatement. Treatment for what is now …

[HTML][HTML] The opioid system and food intake: use of opiate antagonists in treatment of binge eating disorder and abnormal eating behavior

LP Valbrun, V Zvonarev - Journal of clinical medicine research, 2020 - ncbi.nlm.nih.gov
Eating disorders (EDs) and substance use disorders (SUDs) commonly co-occur, especially
in conjunction with affective syndromes, yet little is known about opiate abuse and ED …

Potential contributors to variation in weight‐loss response to liraglutide

CM Webster, N Mittal, EJ Dhurandhar… - Obesity …, 2023 - Wiley Online Library
Obesity treatment requires a chronic state of negative energy balance. Obesity medications
can help with this, increasing long‐term dietary compliance by promoting satiety or reducing …

How negative affect does and does not lead to binge eating—The importance of craving and negative urgency in bulimia nervosa.

N Leenaerts, T Vaessen, S Sunaert… - … and Clinical Science, 2023 - psycnet.apa.org
Studies suggest that negative affect (NA) can trigger binge eating (BE) in patients with
bulimia nervosa (BN). Important factors in this relation between NA and BE could be craving …

Why young women gain weight: A narrative review of influencing factors and possible solutions

M Pegington, DP French, MN Harvie - Obesity reviews, 2020 - Wiley Online Library
Significant weight gain occurs in women during young adulthood, which increases risk of
diseases such as diabetes, cardiovascular disease, and many cancers. This review aims to …