Alzheimer's disease (AD) is a progressive neurodegenerative condition that leads to
memory loss and cognitive impairment over time. It is characterized by protein misfolding as …

Preterm white matter injury (WMI) is a demyelinating disease with high incidence and
mortality in premature infants. Oligodendrocyte cells (OLs) are a specialized glial cell that …

Microglia are the resident immune cells of the central nervous system (CNS) and play a
major role in the regulation of brain homeostasis. To maintain their cellular protein …

Hepatic ischemia–reperfusion injury (HIRI) usually occurs during subtotal hepatectomy and
severely damages liver function during the perioperative period. Endoplasmic reticulum …

Goldfish (Carassius auratus) have been employed as a model organism to investigate the
innate immune system and host-pathogen interactions. A Gram-negative bacterium called …

The pro-tumorigenic properties of heparanase are well documented and established. In
contrast, the role of heparanase 2 (Hpa2), a close homolog of heparanase, in cancer is not …

Background The effects of a solitary neonatal exposure to anesthesia plus surgery
(anesthesia/surgery) on cognitive function and the underlying mechanism in developing …

Multiple sclerosis (MS) is an immune-mediated disorder characterized by focal
demyelination and chronic inflammation of the central nervous system (CNS). Although the …

Ethnopharmacological relevance Alzheimer's disease (AD) is a common type of
neurodegenerative disease with the β-amyloid plaques (Aβ) deposition. Previously …

Endoplasmic reticulum (ER) stress is a significant player in the pathophysiology of various
neurodegenerative and neuropsychiatric disorders. Despite the established link between …