The spinocerebellar ataxias (SCAs) comprise more than 40 autosomal dominant
neurodegenerative disorders that present principally with progressive ataxia. Within the past …

Spinocerebellar ataxia type 2 (SCA2) is an autosomal dominant cerebellar ataxia that
occurs as a consequence of abnormal CAG expansions in the ATXN2 gene. Progressive …

Background Several pieces of evidence have shown the neurotrophic effect of erythropoietin
(EPO) and its introduction in the therapeutic practice of neurological diseases. However, its …

Spinocerebellar ataxia (SCA) is a part of the cerebellar neurodegenerative disease group
that is diverse in genetics and phenotypes. It usually shows autosomal dominant …

Background Saccadic eye movement abnormalities are common in patients with
spinocerebellar ataxia type 2, but it is unclear how these alterations progress over time. The …

Ataxin-2 (human gene symbol ATXN2) acts during stress responses, modulating mRNA
translation and nutrient metabolism. Ataxin-2 knockout mice exhibit progressive obesity …

Abstract Cuban patients with Spinocerebellar Ataxia type 2 (SCA2) have reduced
concentrations of zinc in serum and cerebrospinal fluid (CSF). To assess the effect and …

Abstract Spinocerebellar Ataxia Type 2 (SCA2) is a genetic disorder causing cerebellar
degeneration that result in motor and cognitive alterations. Voxel-based morphometry (VBM) …

Oculomotor abnormalities are common findings in spinocerebellar ataxias (SCAs), a
clinically heterogeneous group of neurodegenerative disorders with an autosomal dominant …

Corticomuscular and intermuscular coherence (CMC, IMC) reflect connectivity between
neuronal activity in the motor cortex measured by electroencephalography (EEG) and …