Eleven shades of PASEF
Introduction The introduction of trapped ion mobility spectrometry (TIMS) in combination with
fast high-resolution time-of-flight (TOF) mass spectrometry to the proteomics field led to a …
fast high-resolution time-of-flight (TOF) mass spectrometry to the proteomics field led to a …
[HTML][HTML] Data-independent acquisition: A milestone and prospect in clinical mass spectrometry-based proteomics
K Fröhlich, M Fahrner, E Brombacher… - Molecular & Cellular …, 2024 - Elsevier
Data-independent acquisition (DIA) has revolutionized the field of mass spectrometry (MS)-
based proteomics over the past few years. DIA stands out for its ability to systematically …
based proteomics over the past few years. DIA stands out for its ability to systematically …
Four-Dimensional Data-Independent Acquisition-Based Proteomic Profiling Combined with Transcriptomic Analysis Reveals the Involvement of the Slym1-SlFHY3 …
P Wang, Z Li, L Zhu, F Mo, F Li, R Lv… - Journal of Agricultural …, 2024 - ACS Publications
In green plants, the chloroplast is responsible for light energy transition and organic
assimilation. However, the molecular mechanisms underlying chloroplast development in …
assimilation. However, the molecular mechanisms underlying chloroplast development in …
GCMSFormer: A Fully Automatic Method for the Resolution of Overlapping Peaks in Gas Chromatography–Mass Spectrometry
Z Guo, Y Fan, C Yu, H Lu, Z Zhang - Analytical Chemistry, 2024 - ACS Publications
Gas chromatography–mass spectrometry (GC–MS) is one of the most important instruments
for analyzing volatile organic compounds. However, the complexity of real samples and the …
for analyzing volatile organic compounds. However, the complexity of real samples and the …
[HTML][HTML] Four-dimensional trapped ion mobility spectrometry proteomics reveals circulating extracellular vesicles encapsulated drivers of nasopharyngeal carcinoma …
P Lu, L Yang, W Chen, K Li, X Chen, S Qu - Talanta, 2025 - Elsevier
Nasopharyngeal carcinoma (NPC) is a head and neck cancer with a high propensity for
early metastatic spread. Emerging evidence shows that extracellular vesicles (EVs) are key …
early metastatic spread. Emerging evidence shows that extracellular vesicles (EVs) are key …
Differential impact of sex on regulation of skeletal muscle mitochondrial function and protein homeostasis by hypoxia‐inducible factor‐1α in normoxia
Abstract Hypoxia‐inducible factor (HIF)‐1α is continuously synthesized and degraded in
normoxia. During hypoxia, HIF1α stabilization restricts cellular/mitochondrial oxygen …
normoxia. During hypoxia, HIF1α stabilization restricts cellular/mitochondrial oxygen …
Liquid-phase separations coupled with ion mobility-mass spectrometry for next-generation biopharmaceutical analysis
DM Makey, BT Ruotolo - Expert Review of Proteomics, 2024 - Taylor & Francis
Introduction The pharmaceutical industry continues to expand its search for innovative
biotherapeutics. The comprehensive characterization of such therapeutics requires many …
biotherapeutics. The comprehensive characterization of such therapeutics requires many …
Advances in the Clinical Application of High-throughput Proteomics
M Cui, F Deng, ML Disis, C Cheng… - … and hypothesis in …, 2024 - pmc.ncbi.nlm.nih.gov
High-throughput proteomics has become an exciting field and a potential frontier of modern
medicine since the early 2000s. While significant progress has been made in the technical …
medicine since the early 2000s. While significant progress has been made in the technical …
Spatial proteomics by trapped ion mobility supported MALDI MS/MS imaging: A first glance into multiplexed and spatial peptide identification
MJ Li, LC Meyer, N Meier, J Witte, M Maldacker… - bioRxiv, 2024 - biorxiv.org
RATIONALE In spatial proteomics, matrix-assisted laser desorption/ionization (MALDI)
imaging enables rapid and cost-effective peptide measurement. Yet, in situ peptide …
imaging enables rapid and cost-effective peptide measurement. Yet, in situ peptide …
Next-Generation Proteomics of Brain Extracellular Vesicles in Schizophrenia Provide New Clues on the Altered Molecular Connectome
C Lorca, M Fernández-Rhodes, JA Sánchez Milán… - Biomedicines, 2024 - mdpi.com
Extracellular vesicles (EVs) are tiny membranous structures that mediate intercellular
communication. The role (s) of these vesicles have been widely investigated in the context of …
communication. The role (s) of these vesicles have been widely investigated in the context of …