Isoniazid: a review of characteristics, properties and analytical methods
GFS Fernandes, HRN Salgado… - Critical reviews in …, 2017 - Taylor & Francis
Isoniazid is a synthetic antimicrobial and one of the most important first-line drugs used in
the treatment of tuberculosis. Since it was introduced in the therapy in 1952, the drug …
the treatment of tuberculosis. Since it was introduced in the therapy in 1952, the drug …
Iontophoresis to overcome the challenge of nail permeation: considerations and optimizations for successful ungual drug delivery
K Chen, V Puri, B Michniak-Kohn - The AAPS journal, 2021 - Springer
Iontophoresis is a widely used drug delivery technique that has been used clinically to
improve permeation through the skin for drugs and other actives in topical formulations. It is …
improve permeation through the skin for drugs and other actives in topical formulations. It is …
Design, synthesis, and structure–activity relationship studies of novel fused heterocycles-linked triazoles with good activity and water solubility
X Cao, Z Sun, Y Cao, R Wang, T Cai… - Journal of medicinal …, 2014 - ACS Publications
Triazoles with fused-heterocycle nuclei were designed and evaluated for their in vitro activity
on the basis of the binding mode of albaconazole using molecular docking, along with SAR …
on the basis of the binding mode of albaconazole using molecular docking, along with SAR …
Hyalugel-integrated liposomes as a novel ocular nanosized delivery system of fluconazole with promising prolonged effect
Fungal infections need long-term therapy with the proper antifungal agent. Despite
effectiveness, Fluconazole (FLZ) ocular delivery is constrained by limited penetration, short …
effectiveness, Fluconazole (FLZ) ocular delivery is constrained by limited penetration, short …
Development and optimization of besifloxacin hydrochloride loaded liposomal gel prepared by thin film hydration method using 32 full factorial design
The objective of this present research work was to develop and optimize a liposomal gel
containing a fourth generation fluoroquinolone antibiotic, besifloxacin hydrochloride (BSF …
containing a fourth generation fluoroquinolone antibiotic, besifloxacin hydrochloride (BSF …
Copper (II) and zinc (II) complexes with the clinically used fluconazole: comparison of antifungal activity and therapeutic potential
Copper (II) and zinc (II) complexes with clinically used antifungal drug fluconazole
(fcz),{[CuCl2 (fcz) 2]. 5H2O} n, 1, and {[ZnCl2 (fcz) 2]· 2C2H5OH} n, 2, were prepared and …
(fcz),{[CuCl2 (fcz) 2]. 5H2O} n, 1, and {[ZnCl2 (fcz) 2]· 2C2H5OH} n, 2, were prepared and …
Development and machine-learning optimization of mucoadhesive nanostructured lipid carriers loaded with fluconazole for treatment of oral candidiasis
The aim of this work was to prepare and optimize mucoadhesive nanostructured lipid carrier
(NLC) impregnated with fluconazole for better management of oral candidiasis. The NLCs …
(NLC) impregnated with fluconazole for better management of oral candidiasis. The NLCs …
Cocrystals of fluconazole with aromatic carboxylic acids: Competition between anhydrous and hydrated solid forms
Through cocrystallization of the broad-spectrum antifungal agent fluconazole (FLZ) with a
number of nutraceuticals, we have isolated three distinct solid forms of the drug, namely …
number of nutraceuticals, we have isolated three distinct solid forms of the drug, namely …
Fluconazole-loaded thermosensitive system: In vitro release, pharmacokinetics and safety study
Fluconazole (FCZ) is a broad spectrum anti-fungal drug and categorized as a BCS class-I
molecule because of its readily soluble and highly permeable properties. Oral delivery of …
molecule because of its readily soluble and highly permeable properties. Oral delivery of …
Novel alkylated azoles as potent antifungals
SK Shrestha, A Garzan… - European Journal of …, 2017 - Elsevier
Fluconazole (FLC) is the drug of choice when it comes to treat fungal infections such as
invasive candidiasis in humans. However, the widespread use of FLC has resulted in the …
invasive candidiasis in humans. However, the widespread use of FLC has resulted in the …