The role of inflammation in cardiovascular disease

MY Henein, S Vancheri, G Longo… - International journal of …, 2022 - mdpi.com
Atherosclerosis is a chronic inflammatory disease, in which the immune system has a
prominent role in its development and progression. Inflammation-induced endothelial …

Coronary calcium score and cardiovascular risk

P Greenland, MJ Blaha, MJ Budoff, R Erbel… - Journal of the American …, 2018 - jacc.org
Coronary artery calcium (CAC) is a highly specific feature of coronary atherosclerosis. On
the basis of single-center and multicenter clinical and population-based studies with short …

Coronary artery calcification and its progression: what does it really mean?

H Mori, S Torii, M Kutyna, A Sakamoto, AV Finn… - JACC: Cardiovascular …, 2018 - jacc.org
Coronary artery calcification is concomitant with the development of advanced
atherosclerosis. Coronary artery calcification pathologically begins as microcalcifications …

Extracellular vesicles in coronary artery disease

CM Boulanger, X Loyer, PE Rautou… - Nature reviews …, 2017 - nature.com
Membrane vesicles released in the extracellular space are composed of a lipid bilayer
enclosing soluble cytosolic material and nuclear components. Extracellular vesicles include …

[HTML][HTML] National Lipid Association recommendations for patient-centered management of dyslipidemia: part 2

TA Jacobson, KC Maki, CE Orringer, PH Jones… - Journal of clinical …, 2015 - Elsevier
Abstract An Expert Panel convened by the National Lipid Association previously developed
a consensus set of recommendations for the patient-centered management of dyslipidemia …

Prevalence of subclinical coronary artery disease in masters endurance athletes with a low atherosclerotic risk profile

A Merghani, V Maestrini, S Rosmini, AT Cox, H Dhutia… - Circulation, 2017 - Am Heart Assoc
Background: Studies in middle-age and older (masters) athletes with atherosclerotic risk
factors for coronary artery disease report higher coronary artery calcium (CAC) scores …

Coronary artery calcification: from mechanism to molecular imaging

T Nakahara, MR Dweck, N Narula, D Pisapia… - JACC: Cardiovascular …, 2017 - jacc.org
Vascular calcification is a hallmark of atherosclerosis. The location, density, and confluence
of calcification may change portions of the arterial conduit to a noncompliant structure …

Why and how to measure aortic valve calcification in patients with aortic stenosis

T Pawade, T Sheth, E Guzzetti, MR Dweck… - JACC: Cardiovascular …, 2019 - jacc.org
The first-line evaluation of aortic stenosis severity is Doppler echocardiography. However, in
up to 40% of patients, resting echocardiographic assessment of aortic stenosis severity is …

Association of statin treatment with progression of coronary atherosclerotic plaque composition

AR Van Rosendael, IJ Van Den Hoogen… - JAMA …, 2021 - jamanetwork.com
Importance The density of atherosclerotic plaque forms the basis for categorizing calcified
and noncalcified morphology of plaques. Objective To assess whether alterations in plaque …

Genesis and growth of extracellular-vesicle-derived microcalcification in atherosclerotic plaques

JD Hutcheson, C Goettsch, S Bertazzo, N Maldonado… - Nature materials, 2016 - nature.com
Clinical evidence links arterial calcification and cardiovascular risk. Finite-element modelling
of the stress distribution within atherosclerotic plaques has suggested that subcellular …