Ischemia-reperfusion (I/R) injury is well-known to be associated with impaired cardiac
function, massive arrhythmias, marked alterations in cardiac metabolism and irreversible …

Obstructive sleep apnea is an underdiagnosed sleep-related breathing disorder affecting
millions of people. Recurrent episodes of apnea/hypopnea result in intermittent hypoxia …

N6-methyladenosine (m6A) methylation in RNA is a dynamic and reversible modification
regulated by methyltransferases and demethylases, which has been reported to participate …

Background/Aims: Long non-coding RNAs (lncRNAs) are theorized to play key roles in the
development of heart diseases. However, the role of lncRNAs in cardiomyocyte apoptosis is …

Aims Myocardial infarction (MI) is a leading cause of death worldwide for which there is no
cure. Percutaneous coronary intervention (PCI) can restore blood supply in a timely manner …

Since the discovery of ischemic pre-and post-conditioning, more than 30 years ago, the
knowledge about the mechanisms and signaling pathways involved in these processes has …

Objective To investigate the effect of lncRNA XIST on apoptosis induced by hypoxia.
Methods We analyzed the expression levels of lncRNA XIST and miR-122-5p using RT …

Apelin is an important contributor to the renin-angiotensin axis, regulating cardiovascular,
metabolic, and neurological functions. Apelin-17 has especially potent cardio-physiological …

Myocardial infarction (MI) injury is a highly lethal syndrome that has, until recently, suffered
from a lack of clinically efficient targeted therapeutics. The cardiac troponin I interacting …

Objectives. Coronary reperfusion procedure leads to ischemia/reperfusion injury of the heart
(IRI). IRI arises from increased degradation of myosin light chains and increased activity of …