Stroke in the 21st Century: A Snapshot of the Burden, Epidemiology, and Quality of Life
ES Donkor - Stroke research and treatment, 2018 - Wiley Online Library
Stroke is ranked as the second leading cause of death worldwide with an annual mortality
rate of about 5.5 million. Not only does the burden of stroke lie in the high mortality but the …
rate of about 5.5 million. Not only does the burden of stroke lie in the high mortality but the …
Sphingosine-1-phosphate (S1P) and S1P signaling pathway modulators, from current insights to future perspectives
GÁ Bravo, RR Cedeño, MP Casadevall… - Cells, 2022 - mdpi.com
Sphingosine-1-phosphate (S1P) and S1P receptors (S1PR) are bioactive lipid molecules
that are ubiquitously expressed in the human body and play an important role in the immune …
that are ubiquitously expressed in the human body and play an important role in the immune …
Treg cell-derived osteopontin promotes microglia-mediated white matter repair after ischemic stroke
L Shi, Z Sun, W Su, F Xu, D Xie, Q Zhang, X Dai, K Iyer… - Immunity, 2021 - cell.com
The precise mechanisms underlying the beneficial effects of regulatory T (Treg) cells on long-
term tissue repair remain elusive. Here, using single-cell RNA sequencing and flow …
term tissue repair remain elusive. Here, using single-cell RNA sequencing and flow …
Direct vascular channels connect skull bone marrow and the brain surface enabling myeloid cell migration
F Herisson, V Frodermann, G Courties, D Rohde… - Nature …, 2018 - nature.com
Innate immune cells recruited to inflammatory sites have short life spans and originate from
the marrow, which is distributed throughout the long and flat bones. While bone marrow …
the marrow, which is distributed throughout the long and flat bones. While bone marrow …
Guidelines for the primary prevention of stroke: a statement for healthcare professionals from the American Heart Association/American Stroke Association
JF Meschia, C Bushnell, B Boden-Albala, LT Braun… - Stroke, 2014 - Am Heart Assoc
The aim of this updated statement is to provide comprehensive and timely evidence-based
recommendations on the prevention of stroke among individuals who have not previously …
recommendations on the prevention of stroke among individuals who have not previously …
Aging and neurodegenerative disease: is the adaptive immune system a friend or foe?
K Mayne, JA White, CE McMurran, FJ Rivera… - Frontiers in aging …, 2020 - frontiersin.org
Neurodegenerative diseases of the central nervous system (CNS) are characterized by
progressive neuronal death and neurological dysfunction, leading to increased disability …
progressive neuronal death and neurological dysfunction, leading to increased disability …
No-reflow phenomenon in the heart and brain
The no-reflow phenomenon refers to the observation that when an organ is made ischemic
by occlusion of a large artery supplying it, restoration of patency in that artery does not …
by occlusion of a large artery supplying it, restoration of patency in that artery does not …
Increased brain-specific MiR-9 and MiR-124 in the serum exosomes of acute ischemic stroke patients
Q Ji, Y Ji, J Peng, X Zhou, X Chen, H Zhao, T Xu… - PloS one, 2016 - journals.plos.org
The aims of this study were to examine the alternation in serum exosome concentrations
and the levels of serum exosomal miR-9 and miR-124, two brain-specific miRNAs, in acute …
and the levels of serum exosomal miR-9 and miR-124, two brain-specific miRNAs, in acute …
COPD and stroke: are systemic inflammation and oxidative stress the missing links?
Chronic obstructive pulmonary disease (COPD) is characterized by progressive airflow
limitation and loss of lung function, and is currently the third largest cause of death in the …
limitation and loss of lung function, and is currently the third largest cause of death in the …
The role of microglia and myeloid immune cells in acute cerebral ischemia
The immune response to acute cerebral ischemia is a major contributor to stroke
pathobiology. The inflammatory response is characterized by the participation of brain …
pathobiology. The inflammatory response is characterized by the participation of brain …