Platelet extracellular vesicles: beyond the blood
Extracellular vesicles (EVs) are a means of cell-to-cell communication and can facilitate the
exchange of a broad array of molecules between adjacent or distant cells. Platelets are …
exchange of a broad array of molecules between adjacent or distant cells. Platelets are …
Store-operated calcium channels
M Prakriya, RS Lewis - Physiological reviews, 2015 - journals.physiology.org
Store-operated calcium channels (SOCs) are a major pathway for calcium signaling in
virtually all metozoan cells and serve a wide variety of functions ranging from gene …
virtually all metozoan cells and serve a wide variety of functions ranging from gene …
Diseases caused by mutations in ORAI1 and STIM1
Ca2+ release‐activated Ca2+ (CRAC) channels mediate a specific form of Ca2+ influx
called store‐operated Ca2+ entry (SOCE) that contributes to the function of many cell types …
called store‐operated Ca2+ entry (SOCE) that contributes to the function of many cell types …
Physiological functions of CRAC channels
SM Emrich, RE Yoast, M Trebak - Annual Review of Physiology, 2022 - annualreviews.org
Store-operated Ca2+ entry (SOCE) is a ubiquitous Ca2+ signaling pathway that is
evolutionarily conserved across eukaryotes. SOCE is triggered physiologically when the …
evolutionarily conserved across eukaryotes. SOCE is triggered physiologically when the …
Microvesicles in vascular homeostasis and diseases
VC Ridger, CM Boulanger… - Thrombosis and …, 2017 - thieme-connect.com
Microvesicles are members of the family of extracellular vesicles shed from the plasma
membrane of activated or apoptotic cells. Microvesicles were initially characterised by their …
membrane of activated or apoptotic cells. Microvesicles were initially characterised by their …
Store-operated calcium entry: Mechanisms and modulation
PG Hogan, A Rao - Biochemical and biophysical research communications, 2015 - Elsevier
Store-operated calcium entry is a central mechanism in cellular calcium signalling and in
maintaining cellular calcium balance. This review traces the history of research on store …
maintaining cellular calcium balance. This review traces the history of research on store …
[HTML][HTML] Inside-out Ca2+ signalling prompted by STIM1 conformational switch
Store-operated Ca 2+ entry mediated by STIM1 and ORAI1 constitutes one of the major Ca
2+ entry routes in mammalian cells. The molecular choreography of STIM1–ORAI1 coupling …
2+ entry routes in mammalian cells. The molecular choreography of STIM1–ORAI1 coupling …
[HTML][HTML] An apical Phe-His pair defines the Orai1-coupling site and its occlusion within STIM1
Ca2+ signal-generation through inter-membrane junctional coupling between endoplasmic
reticulum (ER) STIM proteins and plasma membrane (PM) Orai channels, remains a vital but …
reticulum (ER) STIM proteins and plasma membrane (PM) Orai channels, remains a vital but …
[HTML][HTML] Intertwined and finely balanced: endoplasmic reticulum morphology, dynamics, function, and diseases
HT Perkins, V Allan - Cells, 2021 - mdpi.com
The endoplasmic reticulum (ER) is an organelle that is responsible for many essential
subcellular processes. Interconnected narrow tubules at the periphery and thicker sheet-like …
subcellular processes. Interconnected narrow tubules at the periphery and thicker sheet-like …
Hereditary thrombocytopenias: a growing list of disorders
P Noris, A Pecci - Hematology 2014, the American Society of …, 2017 - ashpublications.org
The introduction of high throughput sequencing (HTS) techniques greatly improved the
knowledge of inherited thrombocytopenias (ITs) over the last few years. A total of 33 different …
knowledge of inherited thrombocytopenias (ITs) over the last few years. A total of 33 different …