Thrombocytopathy and endotheliopathy: crucial contributors to COVID-19 thromboinflammation
The core pathology of coronavirus disease 2019 (COVID-19) is infection of airway cells by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that results in excessive …
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that results in excessive …
Mechanisms and consequences of endothelial cell senescence
Endothelial cells are located at the crucial interface between circulating blood and semi-
solid tissues and have many important roles in maintaining systemic physiological function …
solid tissues and have many important roles in maintaining systemic physiological function …
Blood–brain barrier breakdown: an emerging biomarker of cognitive impairment in normal aging and dementia
B Hussain, C Fang, J Chang - Frontiers in neuroscience, 2021 - frontiersin.org
The blood–brain barrier (BBB) plays a vital role in maintaining the specialized
microenvironment of the neural tissue. It separates the peripheral circulatory system from the …
microenvironment of the neural tissue. It separates the peripheral circulatory system from the …
Oxidative stress, aging, and diseases
I Liguori, G Russo, F Curcio, G Bulli, L Aran… - … interventions in aging, 2018 - Taylor & Francis
Reactive oxygen and nitrogen species (RONS) are produced by several endogenous and
exogenous processes, and their negative effects are neutralized by antioxidant defenses …
exogenous processes, and their negative effects are neutralized by antioxidant defenses …
Mechanisms of vascular aging
Aging of the vasculature plays a central role in morbidity and mortality of older people. To
develop novel treatments for amelioration of unsuccessful vascular aging and prevention of …
develop novel treatments for amelioration of unsuccessful vascular aging and prevention of …
Mechanisms of dysfunction in the aging vasculature and role in age-related disease
AJ Donato, DR Machin, LA Lesniewski - Circulation research, 2018 - Am Heart Assoc
Advancing age promotes cardiovascular disease (CVD), the leading cause of death in the
United States and many developed nations. Two major age-related arterial phenotypes …
United States and many developed nations. Two major age-related arterial phenotypes …
The aging cardiovascular system: understanding it at the cellular and clinical levels
Cardiovascular disease (CVD) presents a great burden for elderly patients, their caregivers,
and health systems. Structural and functional alterations of vessels accumulate throughout …
and health systems. Structural and functional alterations of vessels accumulate throughout …
Hypertension and aging
TW Buford - Ageing research reviews, 2016 - Elsevier
Hypertension is a highly prevalent condition with numerous health risks, and the incidence
of hypertension is greatest among older adults. Traditional discussions of hypertension have …
of hypertension is greatest among older adults. Traditional discussions of hypertension have …
Endothelial dysfunction and angiogenesis impairment in the ageing vasculature
Ageing is the main risk factor for the development of cardiovascular diseases. A central
mechanism by which ageing promotes vascular pathologies is compromising endothelial …
mechanism by which ageing promotes vascular pathologies is compromising endothelial …
The emerging potential of cold atmospheric plasma in skin biology
The maintenance of skin integrity is crucial to ensure the physiological barrier against
exogenous compounds, microorganisms and dehydration but also to fulfill social and …
exogenous compounds, microorganisms and dehydration but also to fulfill social and …