Integrated “lab-on-a-chip” microfluidic systems for isolation, enrichment, and analysis of cancer biomarkers
The liquid biopsy has garnered considerable attention as a complementary clinical tool for
the early detection, molecular characterization and monitoring of cancer over the past …
the early detection, molecular characterization and monitoring of cancer over the past …
Circulating cells with macrophage-like characteristics in cancer: the importance of circulating neoplastic-immune hybrid cells in cancer
Simple Summary In cancer, disseminated neoplastic cells circulating in blood are a source
of tumor DNA, RNA, and protein, which can be harnessed to diagnose, monitor, and better …
of tumor DNA, RNA, and protein, which can be harnessed to diagnose, monitor, and better …
Recent advances in formulation and application of molecular polymer brushes in biomedicine: Therapeutic, diagnostic, and theranostics capabilities
F Adeli, F Abbasi, P Ghandforoushan, HE Külahlı… - Nano Today, 2023 - Elsevier
The applications of nanotechnology in medical sciences, especially in drug and gene
delivery, has experienced unprecedented growth in recent years. The integration of …
delivery, has experienced unprecedented growth in recent years. The integration of …
Intrinsic signalling factors associated with cancer cell-cell fusion
T Dittmar, R Hass - Cell Communication and Signaling, 2023 - Springer
Cellular fusion eg between cancer cells and normal cells represents a stepwise process that
is tightly regulated. During a pre-hybrid preparation program somatic cells and/or cancer …
is tightly regulated. During a pre-hybrid preparation program somatic cells and/or cancer …
Cell-cell fusion in cancer: The next cancer hallmark?
PV Shultes, DT Weaver, DS Tadele… - … International Journal of …, 2024 - Elsevier
In this review, we consider the role of cell-cell fusion in cancer development and progression
through an evolutionary lens. We begin by summarizing the origins of fusion proteins …
through an evolutionary lens. We begin by summarizing the origins of fusion proteins …
Phagocytosis-initiated tumor hybrid cells acquire a c-Myc-mediated quasi-polarization state for immunoevasion and distant dissemination
CW Chou, CN Hung, CHL Chiu, X Tan, M Chen… - Nature …, 2023 - nature.com
While macrophage phagocytosis is an immune defense mechanism against invading
cellular organisms, cancer cells expressing the CD47 ligand send forward signals to repel …
cellular organisms, cancer cells expressing the CD47 ligand send forward signals to repel …
Circulating neoplastic-immune hybrid cells predict metastatic progression in uveal melanoma
MS Parappilly, Y Chin, RM Whalen, AN Anderson… - Cancers, 2022 - mdpi.com
Simple Summary Uveal melanoma is an aggressive cancer that begins in the eye, but often
spreads to distant organs when tumor cells enter the blood. Disease spreads in nearly half …
spreads to distant organs when tumor cells enter the blood. Disease spreads in nearly half …
[HTML][HTML] Uveal melanoma: Comprehensive review of its pathophysiology, diagnosis, treatment, and future perspectives
M Kulbay, E Marcotte, R Remtulla, THA Lau… - Biomedicines, 2024 - mdpi.com
Uveal melanoma (UM) is the most common intraocular malignancy in adults. Recent
advances highlight the role of tumor-derived extracellular vesicles (TEV) and circulating …
advances highlight the role of tumor-derived extracellular vesicles (TEV) and circulating …
Hybrid/atypical forms of circulating tumor cells: current state of the art
EV Kaigorodova, AV Kozik, IS Zavaruev… - Biochemistry …, 2022 - Springer
Cancer is one of the most common diseases worldwide, and its treatment is associated with
many challenges such as drug and radioresistance and formation of metastases. These …
many challenges such as drug and radioresistance and formation of metastases. These …
Tumor hybrid cells: nature and biological significance
MS Tretyakova, AR Subbalakshmi… - Frontiers in cell and …, 2022 - frontiersin.org
Metastasis is the leading cause of cancer death and can be realized through the
phenomenon of tumor cell fusion. The fusion of tumor cells with other tumor or normal cells …
phenomenon of tumor cell fusion. The fusion of tumor cells with other tumor or normal cells …