Polyphenols as potential metabolism mechanisms regulators in liver protection and liver cancer prevention
S Li, S Yin, H Ding, Y Shao, S Zhou, W Pu… - Cell …, 2023 - Wiley Online Library
Background Liver cancer is one of the common malignancies. The dysregulation of
metabolism is a driver of accelerated tumourigenesis. Metabolic changes are well …
metabolism is a driver of accelerated tumourigenesis. Metabolic changes are well …
Identification and management of acute alcohol intoxication
A Mirijello, L Sestito, M Antonelli, A Gasbarrini… - European journal of …, 2023 - Elsevier
Acute alcohol intoxication (AAI) is a harmful clinical condition, potentially life-threatening,
secondary to the intake of large amounts of alcohol. Clinical manifestations of AAI are …
secondary to the intake of large amounts of alcohol. Clinical manifestations of AAI are …
Dihydromyricetin reverses thioacetamide-induced liver fibrosis through inhibiting NF-κB-mediated inflammation and TGF-β1-regulated of PI3K/Akt signaling pathway
Y Zhao, X Liu, C Ding, Y Gu, W Liu - Frontiers in pharmacology, 2021 - frontiersin.org
As a natural active substance, dihydromyricetin (DHM) has been proven to have good
hepatoprotective activity. However, the therapeutic effect of DHM on liver fibrosis, which has …
hepatoprotective activity. However, the therapeutic effect of DHM on liver fibrosis, which has …
[HTML][HTML] Molecular mechanisms and therapeutic implications of dihydromyricetin in liver disease
J Chen, X Wang, T Xia, Y Bi, B Liu, J Fu… - Biomedicine & …, 2021 - Elsevier
Recent studies demonstrated that dihydromyricetin (DHM) has prominent therapeutic effects
on liver injury and liver cancer. By summarizing the current preclinical in vitro and in vivo …
on liver injury and liver cancer. By summarizing the current preclinical in vitro and in vivo …
Dihydromyricetin attenuates D-galactose-induced brain aging of mice via inhibiting oxidative stress and neuroinflammation
J Qian, X Wang, J Cao, W Zhang, C Lu, X Chen - Neuroscience Letters, 2021 - Elsevier
Aging-related especially brain aging-related diseases are heavy health care burdens
worldwide. Natural products with antioxidant and anti-inflammatory properties have been …
worldwide. Natural products with antioxidant and anti-inflammatory properties have been …
Natural compounds: a potential treatment for alcoholic liver disease?
J Yan, Y Nie, M Luo, Z Chen, B He - Frontiers in pharmacology, 2021 - frontiersin.org
Excessive alcohol intake is a direct cause of alcoholic liver disease (ALD). ALD usually
manifests as fatty liver in the initial stage and then develops into alcoholic hepatitis (ASH) …
manifests as fatty liver in the initial stage and then develops into alcoholic hepatitis (ASH) …
Dihydromyricetin improves mitochondrial outcomes in the liver of alcohol-fed mice via the AMPK/Sirt-1/PGC-1α signaling axis
Alcoholic liver disease (ALD), due to the multifactorial damage associated with alcohol
(ethanol) consumption and metabolism, is one of the most prevalent liver diseases in the …
(ethanol) consumption and metabolism, is one of the most prevalent liver diseases in the …
Dihydromyricetin ameliorates liver fibrosis via inhibition of hepatic stellate cells by inducing autophagy and natural killer cell-mediated killing effect
X Zhou, L Yu, M Zhou, P Hou, L Yi, M Mi - Nutrition & Metabolism, 2021 - Springer
Background This study investigated the mechanisms underlying the preventive effect of
dihydromyricetin (DHM) against liver fibrosis involving hepatic stellate cells (HSCs) and …
dihydromyricetin (DHM) against liver fibrosis involving hepatic stellate cells (HSCs) and …
[HTML][HTML] Recent update on application of dihydromyricetin in metabolic related diseases
Y Wang, J Wang, H Xiang, P Ding, T Wu, G Ji - Biomedicine & …, 2022 - Elsevier
As a new type of natural flavonoids, dihydromyricetin (DMY) has attracted more and more
attention. It has a series of pharmacological effects, such as anti-inflammatory, anti-tumor …
attention. It has a series of pharmacological effects, such as anti-inflammatory, anti-tumor …
The role of alcohol metabolism in the pathology of alcohol hangover
The limited number of available studies that examined the pathology of alcohol hangover
focused on biomarkers of alcohol metabolism, oxidative stress and the inflammatory …
focused on biomarkers of alcohol metabolism, oxidative stress and the inflammatory …