Molybdenum is a trace dietary element necessary for the survival of humans. Some
molybdenum-bearing enzymes are involved in key metabolic activities in the human body …

Human bones can suffer from various injuries, such as fractures, bone cancer, among
others, which has initiated research activities towards bone replacement using advanced bio …

Malignant bone tumor is one of the major bone diseases. The treatment of such a bone
disease typically requires the removal of bone tumor and regeneration of tumor‐initiated …

After prosthesis replacement for the treatment of bone tumors, incomplete removal of tumor
cells is the main challenge. Moreover, combating implant-associated infection and …

The challenges in bone tumor therapy are how to repair the large bone defects induced by
surgery and kill all possible residual tumor cells. Compared to cancellous bone defect …

Malignant bone tumors are one of the major serious diseases in clinic. Inferior reconstruction
of new bone and rapid propagation of residual tumor cells are the main challenges to …

The treatment of malignant bone tumors is a significant clinical challenge because it
requires the simultaneous removal of tumor tissues and regeneration of bone defects, and …

Successful repair of critical-sized tumor-resection defects, especially in load-bearing bones,
still remains a major challenge in clinical orthopedics. Titanium (Ti) implants have been …

Bone tissue engineering (BTE) has become a promising method for treating bone defects in
recent decades. Polymers are effective materials currently used in the field of BTE due to …

Denosumab, a fully humanized monoclonal neutralizing antibody, inhibits activation of the
RANK/RANKL/OPG signaling pathway through competitive binding with RANKL, thereby …